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Cellosaurus MCF10CA1d.cl2 (CVCL_6681)

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Cell line name MCF10CA1d.cl2
Accession CVCL_6681
Resource Identification Initiative To cite this cell line use: MCF10CA1d.cl2 (RRID:CVCL_6681)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6679 (MCF10CA1d)
Sex of cell Female
Age at sampling 36Y
Category Transformed cell line
Publications

PubMed=11261825; DOI=10.1023/A:1006461422273
Steven J. Santner, Peter J. Dawson, Larry Tait, Herbert D. Soule, James F. Eliason, Anwar N. Mohamed, Sandra R. Wolman, Gloria H. Heppner, Fred R. Miller;
Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells.
Breast Cancer Res. Treat. 65:101-110(2001)

Cross-references
Encyclopedic resources Wikidata; Q54904444
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number18