Cellosaurus logo
expasy logo

Cellosaurus MCF-7M (CVCL_6672)

[Text][XML][JSON]
Cell line name MCF-7M
Synonyms MCF-7 M
Accession CVCL_6672
Resource Identification Initiative To cite this cell line use: MCF-7M (RRID:CVCL_6672)
Comments Population: Caucasian.
Doubling time: 1.4 days (PubMed=9671407).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=9671407; DOI=10.1038/sj.onc.1201814
Kimberley J. Sweeney, Alexander Swarbrick, Robert Lyndsay Sutherland, Elizabeth A. Musgrove;
Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells.
Oncogene 16:2865-2878(1998)

PubMed=10811993; DOI=10.3892/ijo.16.6.1179
Matthew E. Burow, Christopher B. Weldon, Tung-Chin Chiang, Yan Tang, Bridgette M. Collins-Burow, Kevin Rolfe, Shuan-Fang Li, John A. McLachlan, Barbara S. Beckman;
Differences in protein kinase C and estrogen receptor alpha, beta expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants.
Int. J. Oncol. 16:1179-1187(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6672
Encyclopedic resources Wikidata; Q54904407
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21