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Cellosaurus HTOG (CVCL_6656)

[Text version]
Cell line name HTOG
Accession CVCL_6656
Resource Identification Initiative To cite this cell line use: HTOG (RRID:CVCL_6656)
Comments Population: Japanese.
Characteristics: Established from the granulosa cells of a granulosa-theca cell tumor.
Doubling time: 46.2 hours (Note=At 5th passage), 28.4 hours (Note=At 20th passage), 23.8 hours (Note=At 40th passage) (PubMed=6323807); 25 hours (PubMed=10457904).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Disease Ovarian granulosa cell tumor (NCIt: C6261)
Maligant granulosa cell tumor of the ovary (ORDO: Orphanet_99915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6657 ! HTOT
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=6323807; DOI=10.1093/jnci/72.4.789
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Noburu Kobayashi, Hiroshi Ishikawa;
Establishment and characterization of an estrogen-producing human ovarian granulosa tumor cell line.
J. Natl. Cancer Inst. 72:789-800(1984)

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Isamu Ishiwata, Chieko Ishiwata, Shiro Nozawa, Hiroshi Ishikawa;
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Isao Ono, Takenori Nakaguchi, Hiroshi Ishikawa;
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

PubMed=9436037
Masayuki Soma, Isamu Ishiwata, Chieko Ishiwata, Takenori Nakaguchi, Isao Ono, Kazushige Kiguchi, Hisashi Hashimoto, Toshiaki Tachibana, Hiroshi Ishikawa, Shiro Nozawa;
Tissue reconstruction of gynecologic tumor cells in the rotation culture system.
Hum. Cell 10:175-181(1997)

PubMed=10457904
Isamu Ishiwata, Tadashi Sudo, Kazushige Kiguchi, Hiroshi Ishikawa;
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Jon Christopher Havelock, William E. Rainey, Bruce R. Carr;
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

Cross-references
Encyclopedic resources Wikidata; Q54896671
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17