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Cellosaurus PAGRS-21 (CVCL_6640)

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Cell line name PAGRS-21
Synonyms PA-GRS21; Grs-21
Accession CVCL_6640
Resource Identification Initiative To cite this cell line use: PAGRS-21 (RRID:CVCL_6640)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Female
Age at sampling 26D
Category Transformed cell line
Publications

PubMed=2845413; DOI=10.1073/pnas.85.20.7582; PMCID=PMC282236
Abraham Amsterdam, Arie Zauberman, Gila Meir, Orit Pinhasi-Kimhi, Byung-Sun Suh, Moshe Oren;
Cotransfection of granulosa cells with simian virus 40 and Ha-RAS oncogene generates stable lines capable of induced steroidogenesis.
Proc. Natl. Acad. Sci. U.S.A. 85:7582-7586(1988)

PubMed=2171916; DOI=10.1210/endo-127-5-2489
Byung-Sun Suh, Abraham Amsterdam;
Establishment of highly steroidogenic granulosa cell lines by cotransfection with SV40 and Ha-ras oncogene: induction of steroidogenesis by cyclic adenosine 3'-5'-monophosphate and its suppression by phorbol ester.
Endocrinology 127:2489-2500(1990)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Jon Christopher Havelock, William E. Rainey, Bruce R. Carr;
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

Cross-references
Encyclopedic resources Wikidata; Q54937468
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number14