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Cellosaurus GLHR-15 (CVCL_6636)

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Cell line name GLHR-15
Synonyms GLHR15
Accession CVCL_6636
Resource Identification Initiative To cite this cell line use: GLHR-15 (RRID:CVCL_6636)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=RGD; 3007; Lhcgr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Female
Age at sampling 25D
Category Transformed cell line
Publications

PubMed=1328253; DOI=10.1083/jcb.119.2.439; PMCID=PMC2289662
Byung-Sun Suh, Rolf Sprengel, Iris Keren-Tal, Stanley Himmelhoch, Abraham Amsterdam;
Introduction of a gonadotropin receptor expression plasmid into immortalized granulosa cells leads to reconstitution of hormone-dependent steroidogenesis.
J. Cell Biol. 119:439-450(1992)

PubMed=8961254; DOI=10.1016/S0303-7207(96)03916-0
Natarajagounder Selvaraj, David Israeli, Abraham Amsterdam;
Partial sequencing of the rat steroidogenic acute regulatory protein message from immortalized granulosa cells: regulation by gonadotropins and isoproterenol.
Mol. Cell. Endocrinol. 123:171-177(1996)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Jon Christopher Havelock, William E. Rainey, Bruce R. Carr;
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

Cross-references
Cell line collections (Providers) ABM; T0606
Anatomy/cell type resources BTO; BTO_0002288
Encyclopedic resources Wikidata; Q54835928
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number16