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Cellosaurus CHLA-42 (CVCL_6603)

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Cell line name CHLA-42
Synonyms CHLA_42
Accession CVCL_6603
Resource Identification Initiative To cite this cell line use: CHLA-42 (RRID:CVCL_6603)
Comments Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling 1Y1M
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX
CSF1PO12
D2S133817,20
D3S135816
D5S81811,12
D7S82010,12
D8S11798,13
D13S3178,13
D16S53911,13
D18S5113,14
D19S43313,14
D21S1129,31
FGA23,25
TH017,9.3
TPOX8
vWA17,19

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Web pages Provider; CCR; -; https://www.cccells.org/dl/NB_Data_Sheets/CHLA-42_Cell_Line_Data_Sheet_COGcell_org.pdf
Publications

PubMed=9850071
Nino Keshelava, Robert C. Seeger, Susan Groshen, Charles Patrick Reynolds;
Drug resistance patterns of human neuroblastoma cell lines derived from patients at different phases of therapy.
Cancer Res. 58:5396-5405(1998)

PubMed=11212268
Patricia M. Thompson, John Matthew Maris, Michael D. Hogarty, Robert C. Seeger, Charles Patrick Reynolds, Garrett M. Brodeur, Peter S. White;
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
Cancer Res. 61:679-686(2001)

PubMed=23202128; DOI=10.1038/ng.2493; PMCID=PMC3557959
Mark Sausen, Rebecca J. Leary, Sian Jones, Jian Wu, Charles Patrick Reynolds, Xue-Yuan Liu, Amanda L. Blackford, Giovanni Parmigiani, Luis Alberto Diaz Jr., Nickolas Papadopoulos, Bert Vogelstein ...Show all 14 authors... , Kenneth Wayne Kinzler, Victor E. Velculescu, Michael D. Hogarty; Show fewer authors
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.
Nat. Genet. 45:12-17(2013)

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Ahsan S. Farooqi, Rebecca A. Dagg, L. Mi Rim Choi, Jerry W. Shay, Charles Patrick Reynolds, Loretta M.S. Lau;
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

Cross-references
Encyclopedic resources Wikidata; Q54812498
Polymorphism and mutation databases Cosmic; 930039
Cosmic; 1890123
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16