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Cellosaurus CHLA-42 (CVCL_6603)

[Text version]
Cell line name CHLA-42
Synonyms CHLA_42
Accession CVCL_6603
Resource Identification Initiative To cite this cell line use: CHLA-42 (RRID:CVCL_6603)
Comments Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling 1Y1M
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX
CSF1PO12
D2S133817,20
D3S135816
D5S81811,12
D7S82010,12
D8S11798,13
D13S3178,13
D16S53911,13
D18S5113,14
D19S43313,14
D21S1129,31
FGA23,25
TH017,9.3
TPOX8
vWA17,19

Run an STR similarity search on this cell line
Web pages Provider; CCR; -; https://www.cccells.org/dl/NB_Data_Sheets/CHLA-42_Cell_Line_Data_Sheet_COGcell_org.pdf
Publications

PubMed=9850071
Keshelava N., Seeger R.C., Groshen S., Reynolds C.P.
Drug resistance patterns of human neuroblastoma cell lines derived from patients at different phases of therapy.
Cancer Res. 58:5396-5405(1998)

PubMed=11212268
Thompson P.M., Maris J.M., Hogarty M.D., Seeger R.C., Reynolds C.P., Brodeur G.M., White P.S.
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
Cancer Res. 61:679-686(2001)

PubMed=23202128; DOI=10.1038/ng.2493; PMCID=PMC3557959
Sausen M., Leary R.J., Jones S., Wu J., Reynolds C.P., Liu X.-Y., Blackford A.L., Parmigiani G., Diaz L.A. Jr., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E., Hogarty M.D.
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.
Nat. Genet. 45:12-17(2013)

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P., Lau L.M.S.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

Cross-references
Encyclopedic resources Wikidata; Q54812498
Polymorphism and mutation databases Cosmic; 930039
Cosmic; 1890123
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16