| Cell line name |
CHLA-171 |
|---|
| Synonyms |
CHLA171 |
|---|
| Accession |
CVCL_6597 |
|---|
| Resource Identification Initiative |
To cite this cell line use: CHLA-171 (RRID:CVCL_6597) |
|---|
| Sequence variations |
- Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=11507071).
|
|---|
| Disease |
Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
8Y5M |
|---|
| Category |
Cancer cell line |
|---|
| STR profile |
Source(s): COG
Markers:| Amelogenin | X |
| CSF1PO | 12 |
| D2S1338 | 21,24 |
| D3S1358 | 15 |
| D5S818 | 11,12 |
| D7S820 | 12,13 |
| D8S1179 | 10,14 |
| D13S317 | 8,9 |
| D16S539 | 11,12 |
| D18S51 | 17,19 |
| D19S433 | 14 |
| D21S11 | 29,34.2 |
| FGA | 20,26 |
| TH01 | 7,8.3 |
| TPOX | 8 |
| vWA | 17 |
Run an STR similarity search on this cell line |
|---|
| Web pages |
http://www.cccells.org/dl/NB_Data_Sheets/CHLA-171_Cell_Line_Data_Sheet_COGcell_org.pdf |
|---|
| Publications | PubMed=11212268
Thompson P.M., Maris J.M., Hogarty M.D., Seeger R.C., Reynolds C.P., Brodeur G.M., White P.S.
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
Cancer Res. 61:679-686(2001) PubMed=11507071
Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C., Gomer C.J., Triche T.J., Reynolds C.P.
Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines.
Cancer Res. 61:6185-6193(2001) PubMed=16822308; DOI=10.1186/1471-2407-6-177
Dam V., Morgan B.T., Mazanek P., Hogarty M.D.
Mutations in PIK3CA are infrequent in neuroblastoma.
BMC Cancer 6:177.1-177.10(2006) PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P., Lau L.M.S.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014) |
|---|
| Cross-references |
|---|
| Encyclopedic resources |
Wikidata; Q54812171
|
|---|
| Polymorphism and mutation databases |
Cosmic; 930060
Cosmic; 1019949
IARC_TP53; 23826
|
|---|
| Entry history |
|---|
| Entry creation | 04-Apr-2012 |
|---|
| Last entry update | 21-Mar-2023 |
|---|
| Version number | 15 |
|---|
