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Cellosaurus BG1 (CVCL_6570)

[Text version]
Cell line name BG1
Synonyms BG-1; BG-I; Bowman Gray-1; BG-1 FR
Accession CVCL_6570
Resource Identification Initiative To cite this cell line use: BG1 (RRID:CVCL_6570)
Comments Problematic cell line: Partially contaminated. Some stocks are contaminated by MCF-7 (PubMed=22710073; PubMed=25321415).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00456.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease Ovarian adenocarcinoma (NCIt: C7700)
Adenocarcinoma of ovary (ORDO: Orphanet_213504)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Millipore=SCC415; PubMed=25321415

Markers:
AmelogeninX
CSF1PO10,11
D2S133822,23
D3S135816,17
D5S81812
D7S82012
D8S117912,13
D13S31710
D16S5399,11
D18S5112,15
D19S43313,15
D21S1129,33.2 (PubMed=25321415)
29,33.2,34.2 (Millipore=SCC415)
FGA20,24
Penta D11,12
Penta E7,12
TH018,9.3
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2910432; DOI=10.1002/1097-0142(19890115)63:2<280::AID-CNCR2820630213>3.0.CO;2-N
Kim R. Geisinger, Timothy E. Kute, Mark J. Pettenati, Charles E. Welander, Yvonne Dennard, Lee Ann Collins, Michael E. Berens;
Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors.
Cancer 63:280-288(1989)

PubMed=9698466; DOI=10.1006/gyno.1998.5039
George Larry Maxwell, John I. Risinger, Betty Tong, Heather Shaw, J. Carl Barrett, Andrew Berchuck, P. Andrew Futreal;
Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.
Gynecol. Oncol. 70:13-16(1998)

PubMed=9769151; DOI=10.1007/s11626-996-0015-9
William S. Baldwin, Sylvia Curtis Hewitt, Clay A. Cauthen, John I. Risinger, Kenneth S. Korach, J. Carl Barrett;
BG-1 ovarian cell line: an alternative model for examining estrogen-dependent growth in vitro.
In Vitro Cell. Dev. Biol. Anim. 34:649-654(1998)

PubMed=22328975; DOI=10.1158/2159-8290.CD-11-0170; PMCID=PMC3274821
Aphrothiti J. Hanrahan, Nikolaus Schultz, Maggie L. Westfal, Rita A. Sakr, Dilip D. Giri, Stefano Scarperi, Manickam Janakiraman, Narciso Olvera, Ellen V. Stevens, Qing-Bai She, Carol Aghajanian ...Show all 20 authors... , Tari A. King, Elisa de Stanchina, David R. Spriggs, Adriana Heguy, Barry Stephen Taylor, Chris Sander, Neal Rosen, Douglas A. Levine, David B. Solit; Show fewer authors
Genomic complexity and AKT dependence in serous ovarian cancer.
Cancer Discov. 2:56-67(2012)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=25321415; DOI=10.1210/me.2014-1229; PMCID=PMC4250366
Yin Li, Yukitomo Arao, Julie M. Hall, Sandra Sczerba Burkett, Li-Wen Liu, Kevin Gerrish, Vincent Cavailles, Kenneth S. Korach;
Research resource: STR DNA profile and gene expression comparisons of human BG-1 cells and a BG-1/MCF-7 clonal variant.
Mol. Endocrinol. 28:2072-2081(2014)

Cross-references
Cell line collections (Providers) CancerTools; 153873
Millipore; SCC415
Anatomy/cell type resources BTO; BTO_0000177
Biological sample resources BioSample; SAMN03151838
Chemistry resources ChEMBL-Cells; CHEMBL3307815
ChEMBL-Targets; CHEMBL613537
PubChem_Cell_line; CVCL_6570
Encyclopedic resources Wikidata; Q54796229
Gene expression databases GEO; GSM851910
Polymorphism and mutation databases Cosmic; 844351
Cosmic; 1709248
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25