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Cellosaurus (CVCL_6487)

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Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:8806; PDHA1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0006 (THP-1)
Children:
CVCL_RG42 (J26-A3)CVCL_RG43 (J26-B7)CVCL_XY24 (J26-G)
CVCL_V081 (J26Cw3)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
Entry history
Entry creation25-Jun-2026
Last entry update25-Jun-2026
Version number1