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Cellosaurus T235 (CVCL_6478)

[Text version]
Cell line name T235
Synonyms ATC235
Accession CVCL_6478
Resource Identification Initiative To cite this cell line use: T235 (RRID:CVCL_6478)
Comments Omics: Transcriptomics; Microarray.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
STR profile Source(s): PubMed=18713817; PubMed=30737244

Markers:
AmelogeninX
CSF1PO12
D3S135814
D5S8189,12
D7S8208,10
D8S117911,14
D13S31711,14
D16S53911,12
D18S5113,19
D21S1129
FGA21,23
TH016
TPOX8,12
vWA17,18

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Publications

PubMed=17406368; DOI=10.1038/sj.bjc.6603578; PMCID=PMC2360140
Ricardo F. Rodrigues, Lucia Roque, Tami Krug, Valeriano Leite;
Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines.
Br. J. Cancer 96:1237-1245(2007)

PubMed=18713817; DOI=10.1210/jc.2008-1102; PMCID=PMC2582569
Rebecca E. Schweppe, Joshua P. Klopper, Christopher T. Korch, Umarani Pugazhenthi, Miriam Benezra, Jeffrey A. Knauf, James Alexander Fagin, Laura A. Marlow, John Alton Copland 3rd, Robert Christian Smallridge, Bryan R. Haugen;
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

PubMed=23833040; DOI=10.1210/jc.2013-2383; PMCID=PMC3763971
Inigo Landa, Ian Ganly, Timothy A. Chan, Norisato Mitsutake, Michiko Matsuse, Tihana Ibrahimpasic, Ronald A. Ghossein, James Alexander Fagin;
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Inigo Landa, Nikita Pozdeyev, Christopher T. Korch, Laura A. Marlow, Robert Christian Smallridge, John Alton Copland 3rd, Ying C. Henderson, Stephen Y. Lai, Gary L. Clayman, Naoyoshi Onoda, Aik-Choon Tan ...Show all 16 authors... , Maria E.R. Garcia-Rendueles, Jeffrey A. Knauf, Bryan R. Haugen, James Alexander Fagin, Rebecca E. Schweppe; Show fewer authors
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6478
Encyclopedic resources Wikidata; Q54971452
Polymorphism and mutation databases Cosmic; 1239957
Cosmic; 2054078
Cosmic; 2186781
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23