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Cellosaurus VK2/E6E7 (CVCL_6471)

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Cell line name VK2/E6E7
Synonyms Vk2/E6E7; VK-2/E6E7; VK2 (E6/E7); VK2
Accession CVCL_6471
Resource Identification Initiative To cite this cell line use: VK2/E6E7 (RRID:CVCL_6471)
Comments Doubling time: ~24 hours (ATCC=CRL-2616).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Vagina, mucosa; UBERON=UBERON_0004983.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 32Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2616

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,24
D3S135817
D5S8189,10
D7S82010,11
D8S117912,13
D13S3179,12
D16S5399
D18S5117,19
D19S43311,12
D21S1129,31.2
FGA19,25
Penta D9,12
Penta E7,8
TH017,9.3
TPOX11
vWA16

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Publications

PubMed=9314589; DOI=10.1095/biolreprod57.4.847
Raina N. Fichorova, James George Rheinwald, Deborah J. Anderson;
Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins.
Biol. Reprod. 57:847-855(1997)

Cross-references
Cell line collections (Providers) ATCC; CRL-2616
Cell line databases/resources CLO; CLO_0009535
Anatomy/cell type resources BTO; BTO_0005683
Biological sample resources BioSample; SAMN03471675
Encyclopedic resources Wikidata; Q54993191
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number23