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Cellosaurus C1R-sB7 (CVCL_6375)

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Cell line name C1R-sB7
Accession CVCL_6375
Resource Identification Initiative To cite this cell line use: C1R-sB7 (RRID:CVCL_6375)
Comments Population: Caucasian.
Characteristics: Secrete HLA-B allele B*07 but does not express surface B*07 (ATCC=CRL-2370).
Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4932; HLA-B (Note=Allele B*07. Soluble form without TM and cytoplasmic domains).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3714 (HMy2.C1R)
Sex of cell Female
Age at sampling 33Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2370

Markers:
AmelogeninX
CSF1PO6,10
D2S133817
D3S135816
D5S81810,13
D7S8207,12
D8S117915
D13S31711,13
D16S5399,13
D18S5114,16
D19S43314,15
D21S1129,30
FGA20,21
Penta D10
Penta E12
TH018
TPOX8
vWA17

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Publications

PubMed=7960968; DOI=10.1016/0198-8859(94)90074-4
Debra D. Hiraki, Klaus See-Tho, Ellen Filvaroff, Shalini Krishnaswamy, William de Bello, Behnaz Taidi-Laskowski, Frank Carl Grumet;
Bioengineered soluble HLA-B7. Genesis, characterization, and occurrence of dimerization.
Hum. Immunol. 40:235-246(1994)

Cross-references
Cell line collections (Providers) ATCC; CRL-2370
NCBI_Iran; C525
Cell line databases/resources CLO; CLO_0002104
Encyclopedic resources Wikidata; Q54807885
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number19