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Cellosaurus 293/CHE-Fc (CVCL_6352)

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Cell line name 293/CHE-Fc
Accession CVCL_6352
Resource Identification Initiative To cite this cell line use: 293/CHE-Fc (RRID:CVCL_6352)
Comments Characteristics: Transfected with CHE-Fc, a recombinant soluble chimeric protein fusion of influenza C hemagglutinin-esterase with human IgG1 Fc. It is useful as a probe to detect 9-O-acetylated sialic acids (PubMed=8052660).
Doubling time: ~24 hours (ATCC=CRL-2368).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03465; Influenza C virus (strain C/California/1978) hemagglutinin-esterase-fusion glycoprotein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2368

Markers:
AmelogeninX
CSF1PO12
D2S133819
D3S135815,17
D5S8188
D7S82011,12
D8S117912,14
D13S31712,14
D16S5399,13
D18S5117,18
D19S43315,18
D21S1128,30.2
FGA23
Penta D9,10
Penta E7,15
TH017,9.3
TPOX11
vWA16,19

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Publications

PubMed=8052660; DOI=10.1073/pnas.91.16.7782; PMCID=PMC44486
Andre Klein, Murli Krishna, Nissi Mary Varki, Ajit Varki;
9-O-acetylated sialic acids have widespread but selective expression: analysis using a chimeric dual-function probe derived from influenza C hemagglutinin-esterase.
Proc. Natl. Acad. Sci. U.S.A. 91:7782-7786(1994)

Cross-references
Cell line collections (Providers) ATCC; CRL-2368
Cell line databases/resources CLO; CLO_0001234
Encyclopedic resources Wikidata; Q54583932
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number18