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Cellosaurus eEnd.2 (CVCL_6274)

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Cell line name eEnd.2
Accession CVCL_6274
Resource Identification Initiative To cite this cell line use: eEnd.2 (RRID:CVCL_6274)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03077; Murine polyomavirus (strain A2) (MPyV) middle T antigen (PyMT).
Transformant: NCBI_TaxID; 10636; Murine polyomavirus (strain A2) (MPyV).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=2736622; DOI=10.1016/0092-8674(89)90343-7
R. Lindsay Williams, Werner Risau, Hans-Gunther Zerwes, Hannes Drexler, Adriano Aguzzi, Erwin Friedrich Wagner;
Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment.
Cell 57:1053-1063(1989)

PubMed=2379237; DOI=10.1016/0092-8674(90)90009-4
Roberto Montesano, Michael Sean Pepper, Uta Mohle-Steinlein, Werner Risau, Erwin Friedrich Wagner, Lelio Orci;
Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene.
Cell 62:435-445(1990)

Cross-references
Encyclopedic resources Wikidata; Q54832043
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number12