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Cellosaurus SK-RC-61 (CVCL_6208)

[Text version]
Cell line name SK-RC-61
Synonyms SK RC 61; SKRC61
Accession CVCL_6208
Resource Identification Initiative To cite this cell line use: SK-RC-61 (RRID:CVCL_6208)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Doubling time: 48 hours (PubMed=2386958).
Miscellaneous: STR profile, metastatic site and age/sex of donor from MSKCC antibody and bioresource core facility.
Derived from site: Metastatic; Adrenal gland; UBERON=UBERON_0002369.
Sequence variations
  • Mutation; HGNC; 12687; VHL; Simple; p.Val130Leu (c.388G>C); ClinVar=VCV000002229; Zygosity=Unspecified (PubMed=7915601).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX
CSF1PO11,12
D2S133823
D3S135817
D5S8189,12
D7S82011
D8S117912,15
D13S31712
D16S5399
D18S5112
D19S43314,16
D21S1129
FGA24
TH019.3
TPOX8,9
vWA16,17

Run an STR similarity search on this cell line
Web pages https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-p-primary-human-renal-cell-carcinoma-rcc-cell-line-collection
Publications

PubMed=2386958
Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.
Establishment and characterization of human renal cancer and normal kidney cell lines.
Cancer Res. 50:5531-5536(1990)

PubMed=7915601; DOI=10.1038/ng0594-85
Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., Linehan W.M.
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6208
Encyclopedic resources Wikidata; Q54954614
Polymorphism and mutation databases Cosmic; 972920
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21