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Cellosaurus SK-MEL-192 (CVCL_6101)

[Text version]
Cell line name SK-MEL-192
Synonyms SK-Mel-192; SKMEL-192; SKMEL192
Accession CVCL_6101
Resource Identification Initiative To cite this cell line use: SK-MEL-192 (RRID:CVCL_6101)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Not specified.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=18505964; DOI=10.1093/jnci/djn157; PMCID=PMC4410798
Daniel E. Freedberg, Sushilaben Harkisandas Rigas, Julie E. Russak, Wei-Ming Gai, Margarita E. Kaplow, Iman Osman, Faye Turner, Juliette A. Randerson-Moor, Alan N. Houghton, Klaus J. Busam, David Timothy Bishop ...Show all 14 authors... , Boris C. Bastian, Julia A. Newton-Bishop, David Polsky; Show fewer authors
Frequent p16-independent inactivation of p14ARF in human melanoma.
J. Natl. Cancer Inst. 100:784-795(2008)

PubMed=21343389; DOI=10.1158/0008-5472.CAN-10-2958; PMCID=PMC3070783
Amy E. Rose, Laura Poliseno, Jin-Hua Wang, Michael Clark, Alexander Pearlman, Gui-Min Wang, Eleazar Carmelo Vega y Saenz de Miera, Ratna Medicherla, Paul J. Christos, Richard Shapiro, Anna Pavlick ...Show all 17 authors... , Farbod Darvishian, Jiri Zavadil, David Polsky, Eva Hernando, Harry Ostrer, Iman Osman; Show fewer authors
Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.
Cancer Res. 71:2561-2571(2011)

PubMed=21725359; DOI=10.1038/onc.2011.250; PMCID=PMC3267014
Feng Xing, Yogindra Persaud, Christine A. Pratilas, Barry Stephen Taylor, Manickam Janakiraman, Qing-Bai She, Humilidad F. Gallardo, C. Liu, Taha Merghoub, Blake E. Hefter, Igor Dolgalev ...Show all 19 authors... , Agnes J. Viale, Adriana Heguy, Elisa de Stanchina, David Cobrinik, Gideon Bollag, Jedd D. Wolchok, Alan N. Houghton, David B. Solit; Show fewer authors
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF.
Oncogene 31:446-457(2012)

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625; PMCID=PMC4005042
Moriah Heller Nissan, Christine A. Pratilas, Alexis M. Jones, Ricardo Ramirez, Helen Won, Cai-Lian Liu, Shakuntala Tiwari, Li Kong, Aphrothiti J. Hanrahan, Zhan Yao, Taha Merghoub ...Show all 19 authors... , Antoni Ribas, Paul B. Chapman, Rona D. Yaeger, Barry Stephen Taylor, Nikolaus Schultz, Michael F. Berger, Neal Rosen, David B. Solit; Show fewer authors
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6101
Lonza; 1341
Encyclopedic resources Wikidata; Q54953899
Gene expression databases GEO; GSM555131
GEO; GSM555184
Polymorphism and mutation databases Cosmic; 685211
Cosmic; 1122262
Cosmic; 1669189
Progenetix; CVCL_6101
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number24