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Cellosaurus SK-MEL-176 (CVCL_6092)

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Cell line name SK-MEL-176
Synonyms SK-Mel-176; SK-MEL 176; SKMEL-176
Accession CVCL_6092
Resource Identification Initiative To cite this cell line use: SK-MEL-176 (RRID:CVCL_6092)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=3972469; DOI=10.1002/ijc.2910350215
Francoise M.Y.R. Vessiere-Louveaux, Martine Darville, Alexander Knuth, Thierry Boon;
Use of irradiated mouse fibroblasts to improve the cloning and adaptation to culture of human melanoma cells.
Int. J. Cancer 35:231-235(1985)

PubMed=21725359; DOI=10.1038/onc.2011.250; PMCID=PMC3267014
Feng Xing, Yogindra Persaud, Christine A. Pratilas, Barry Stephen Taylor, Manickam Janakiraman, Qing-Bai She, Humilidad F. Gallardo, Cai-Lian Liu, Taha Merghoub, Blake E. Hefter, Igor Dolgalev ...Show all 19 authors... , Agnes J. Viale, Adriana Heguy, Elisa de Stanchina, David Cobrinik, Gideon Bollag, Jedd David Wolchok, Alan N. Houghton, David B. Solit; Show fewer authors
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF.
Oncogene 31:446-457(2012)

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625; PMCID=PMC4005042
Moriah Heller Nissan, Christine A. Pratilas, Alexis M. Jones, Ricardo Ramirez, Helen Won, Cai-Lian Liu, Shakuntala Tiwari, Li Kong, Aphrothiti J. Hanrahan, Zhan Yao, Taha Merghoub ...Show all 19 authors... , Antoni Ribas, Paul B. Chapman, Rona D. Yaeger, Barry Stephen Taylor, Nikolaus Schultz, Michael F. Berger, Neal Rosen, David B. Solit; Show fewer authors
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Encyclopedic resources Wikidata; Q54953864
Polymorphism and mutation databases Cosmic; 1669180
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14