Cellosaurus cell line TR-BBB6 (CVCL

Cellosaurus TR-BBB6 (CVCL_5U72)

Cross-references
Cell line name	TR-BBB6
Synonyms	TR-BBB 6
Accession	CVCL_5U72
Resource Identification Initiative	To cite this cell line use: TR-BBB6 (RRID:CVCL_5U72)
Comments	Genetic integration: Method=Transgenic rat; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58). Derived from site: In situ; Brain, cerebrum; UBERON=UBERON_0001893. Cell type: Capillary endothelial cell; CL=CL_0002144.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Wistar SV40-tsA58 transgenic.
Originate from same individual	CVCL_5U70 ! TR-BBB1 CVCL_5U71 ! TR-BBB5
Sex of cell	Male
Age at sampling	Age unspecified
Category	Conditionally immortalized cell line
Publications	PubMed=11328662; DOI=10.3109/10611860008997912 Ken-ichi Hosoya, Tadayuki Takashima, Kazuhiro Tetsuka, Tatsuya Nagura, Sumio Ohtsuki, Hitomi Takanaga, Masatsugu Ueda, Nobuyuki Yanai, Masuo Obinata, Tetsuya Terasaki; mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting. J. Drug Target. 8:357-370(2000) PubMed=11520047; DOI=10.1006/bbrc.2001.5247 Masuo Obinata; Possible applications of conditionally immortalized tissue cell lines with differentiation functions. Biochem. Biophys. Res. Commun. 286:667-672(2001) Patent=US20020045254 Ken-ichi Hosoya, Tetsuya Terasaki, Masatsugu Ueda, Masuo Obinata; Established cells. Patent number US20020045254, 18-Apr-2002 PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456 Masuo Obinata; The immortalized cell lines with differentiation potentials: their establishment and possible application. Cancer Sci. 98:275-283(2007)
Encyclopedic resources	Wikidata; Q54972878
Entry history
Entry creation	23-Feb-2016
Last entry update	14-Aug-2025
Version number	9