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Cellosaurus L.14 (CVCL_5U28)

[Text version]
Cell line name L.14
Synonyms L-14; L14; Line 14
Accession CVCL_5U28
Resource Identification Initiative To cite this cell line use: L.14 (RRID:CVCL_5U28)
Comments Characteristics: IL2 dependent.
Characteristics: Recognizes the terpolymer Glu60-Ala30-Tyr10, known as GAT.
Cell type: Helper T-cell; CL=CL_0000912.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_C4UP (14-1.6)
Category Factor-dependent cell line
Publications

DOI=10.1016/B978-0-12-249920-3.50038-7
Jacques Theze, Masao Kimoto, Marie-Lise Gougeon, Jean-Louis Moreau, Gerard Somme, Lise Leclercq, C. Garrison Fathman;
T cell lines and T cell clones bearing cross-reactive idiotype.
(In book chapter) Isolation, characterization and utilization of T lymphocyte clones; Fathman, C. Garrison & Fitch, Frank Wesley (eds.); pp.397-404; Academic Press; New York; USA (1982)

PubMed=2408903; DOI=10.1002/eji.1830150716
Georges Bismuth, Jean-Louis Moreau, Gerard Somme, Maryse Duphot, Alice Dautry-Varsat, Richard J. Robb, Jacques Theze;
Regulation of interleukin 2 (IL2) receptor expression: IL2 as an inducing signal for the expression of its own receptor on a murine T helper cell line.
Eur. J. Immunol. 15:723-727(1985)

PubMed=3100639; DOI=10.4049/jimmunol.138.5.1485
Ashok Kumar, Jean-Louis Moreau, Dana Baran, Jacques Theze;
Evidence for negative regulation of T cell growth by low affinity interleukin 2 receptors.
J. Immunol. 138:1485-1493(1987)

PubMed=2523424; DOI=10.4049/jimmunol.142.9.3113
Dragana Lj Jankovic, Maryse Gibert, Dana Baran, Junichi Ohara, William Erwin Paul, Jacques Theze;
Activation by IL-2, but not IL-4, up-regulates the expression of the p55 subunit of the IL-2 receptor on IL-2- and IL-4-dependent T cell lines.
J. Immunol. 142:3113-3120(1989)

Cross-references
Encyclopedic resources Wikidata; Q54900862
Entry history
Entry creation23-Feb-2016
Last entry update29-Jun-2023
Version number7