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Cellosaurus MG20 (CVCL_5T82)

[Text version]
Cell line name MG20
Accession CVCL_5T82
Resource Identification Initiative To cite this cell line use: MG20 (RRID:CVCL_5T82)
Comments Characteristics: Overexpresses prion protein (PubMed=17121794).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: Myc.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Microglial cell; CL=CL_0000129.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Tga20.
Sex of cell Sex unspecified
Age at sampling <1D
Category Transformed cell line
Publications

PubMed=17121794; DOI=10.1128/JVI.01379-06; PMCID=PMC1797525
Yoshifumi Iwamaru, Takato Takenouchi, Kazumasa Ogihara, Megumi Hoshino, Masuhiro Takata, Morikazu Imamura, Yuichi Tagawa, Hiroko Hayashi-Kato, Yuko Ushiki-Kaku, Yoshihisa Shimizu, Hiroyuki Okada ...Show all 14 authors... , Morikazu Shinagawa, Hiroshi Kitani, Takashi Yokoyama; Show fewer authors
Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strains.
J. Virol. 81:1524-1527(2007)

Cross-references
Encyclopedic resources Wikidata; Q54905416
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number8