Cellosaurus cell line (CVCL

Cellosaurus (CVCL_5J39)

Cross-references
Synonyms	B-1
Comments	Doubling time: 40-50 hours (PubMed=1648979). Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Gene fusion; HGNC; HGNC:7135; AFF1 + HGNC; HGNC:7132; KMT2A; Name(s)=KMT2A-AFF1, MLL-AFF1, ALL-1/AF4; Note=In frame (PubMed=1423625; PubMed=8358709).
Disease	Childhood B acute lymphoblastic leukemia (NCIt: C9140) B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged (NCIt: C80342) B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) (ORDO: Orphanet_585918)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	14Y
Category	Cancer cell line
Publications	Allan Balmain; Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7. Cell 61:407-417(1990) John Oval, Oliver W. Jones, Mark Montoya, Raymond Taetle; Characterization of a factor-dependent acute leukemia cell line with translocation (3;3)(q21;q26). Blood 76:1369-1374(1990) Expression of oligodendrocyte-associated genes in cell lines derived from human gliomas and neuroblastomas. Cancer Res. 53:170-175(1993) Nicholas Constantin Popescu; Novel genomic imbalances and chromosome translocations involving c-myc gene in Burkitt's lymphoma. Leukemia 15:1582-1588(2001)
Encyclopedic resources	Wikidata; Q54752263
Polymorphism and mutation databases	Cosmic; 1037743 Cosmic; 1524791 Cosmic; 2393012
Entry history
Entry creation	15-Nov-2017
Last entry update	19-Dec-2024
Version number	14