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Cellosaurus MCF-7-luc-F5 (CVCL_5J35)

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Cell line name MCF-7-luc-F5
Accession CVCL_5J35
Resource Identification Initiative To cite this cell line use: MCF-7-luc-F5 (RRID:CVCL_5J35)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Discontinued: Revvity/PerkinElmer; 119262; true.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

CLPUB00781
Darlene E. Jenkins, Yvette S. Hornig, Yoko A. Oei, Shang-Fan Yu, Joan M. Dusich, Anthony F. Purchio;
Luciferase-expressing MCF-7-luc-F5 human breast cancer cells used to monitor mammary fat pad tumor growth and metastasis in vivo in nude-beige mice.
Cancer Res. 64 Suppl. 7:1179-1180(2004)

Cross-references
Cell line collections (Providers) Revvity/PerkinElmer; 119262
Cell line databases/resources cancercelllines; CVCL_5J35
Encyclopedic resources Wikidata; Q54904334
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number17