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Cellosaurus HEK293-Nav 1.3 (CVCL_5I43)

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Cell line name HEK293-Nav 1.3
Synonyms NaV 1.3 HEK
Accession CVCL_5I43
Resource Identification Initiative To cite this cell line use: HEK293-Nav 1.3 (RRID:CVCL_5I43)
Comments Genetic integration: Method=Transfection; Gene=RGD; 3635; Scn3a.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Children:
CVCL_5I44 (NaV 1.3 KIR 2.1)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=11487618; DOI=10.1523/JNEUROSCI.21-16-05952.2001; PMCID=PMC6763143
Theodore R. Cummins, Fabio Aglieco, Mathurkrisnan Renganathan, Raimund I. Herzog, Sulayman D. Dib-Hajj, Stephen George Waxman;
Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons.
J. Neurosci. 21:5952-5961(2001)

Cross-references
Encyclopedic resources Wikidata; Q54882459
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number12