Cell line name |
COSB |
Accession |
CVCL_5I33 |
Resource Identification Initiative |
To cite this cell line use: COSB (RRID:CVCL_5I33) |
Sequence variations |
- Mutation; VGNC; VGNC:84862; EP300; Simple; p.Asn1570fs (c.4704dupG); Zygosity=Heterozygous (from parent cell line).
- Mutation; VGNC; VGNC:44555; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); Zygosity=Homozygous (from parent cell line).
- Mutation; VGNC; VGNC:47719; TP53; Simple; p.Ala150fs (c.447delG); Zygosity=Heterozygous (from parent cell line).
- Mutation; VGNC; VGNC:47719; TP53; Simple; p.Leu184Phe (c.550C>T); Zygosity=Heterozygous (from parent cell line).
|
Disease |
Canine hemangiosarcoma (NCIt: C122783) |
Species of origin |
Canis lupus familiaris (Dog) (Canis familiaris)
(NCBI Taxonomy: 9615)
Breed/subspecies: German Shepherd; VBO=VBO_0200577. |
Hierarchy |
Parent: CVCL_0C95 (SB-HSA) |
Sex of cell |
Male |
Age at sampling |
9Y |
Category |
Cancer cell line |
Publications | PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199 Jong-Hyuk Kim, Aric M. Frantz, Katie L. Anderson, Ashley J. Graef, Milcah C. Scott, Sally Robinson, Leslie C. Sharkey, Timothy D. O'Brien, Erin B. Dickerson, Jaime F. Modiano; Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment. Exp. Cell Res. 323:155-164(2014) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54814331
|
Entry history |
Entry creation | 14-Dec-2015 |
Last entry update | 19-Dec-2024 |
Version number | 8 |
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