Cellosaurus cell line HMO6 (CVCL

Cellosaurus HMO6 (CVCL_5G94)

Cross-references
Cell line name	HMO6
Synonyms	HMO6.A1; HM06.A1
Accession	CVCL_5G94
Resource Identification Initiative	To cite this cell line use: HMO6 (RRID:CVCL_5G94)
Comments	Group: Patented cell line. Doubling time: 34.5 hours (PubMed=11741401). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus 29 v-Myc. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: v-Myc. Derived from site: In situ; Brain; UBERON=UBERON_0000955. Cell type: Microglial cell; CL=CL_0000129.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Category	Transformed cell line
Web pages	Info; ResearchGate; -; https://www.researchgate.net/post/Human_Microglia_Cell_Line
Publications	PubMed=11741401; DOI=10.1006/nbdi.2001.0437 Atsushi Nagai, Eriko Nakagawa, Kozo Hatori, Hyun B. Choi, James G. McLarnon, May Ann Lee, Seung U. Kim; Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines. Neurobiol. Dis. 8:1057-1068(2001) Patent=US6780641 Seung U. Kim; Immortalized human microglia cell line. Patent number US6780641, 24-Aug-2004 PubMed=15957187; DOI=10.1002/jnr.20478 Atsushi Nagai, Seiji Mishima, Yuri Ishida, Hiroto Ishikura, Takayuki Harada, Shotai Kobayashi, Seung U. Kim; Immortalized human microglial cell line: phenotypic expression. J. Neurosci. Res. 81:342-348(2005) PubMed=22651808; DOI=10.1186/1742-2094-9-115; PMCID=PMC3407712 Branden Stansley, Jan Post, Kenneth Hensley; A comparative review of cell culture systems for the study of microglial biology in Alzheimer's disease. J. Neuroinflammation 9:115.1-115.8(2012)
Encyclopedic resources	Wikidata; Q54889943
Gene expression databases	GEO; GSE28642
Entry history
Entry creation	14-Dec-2015
Last entry update	14-Aug-2025
Version number	12