Cell line name |
U-251MG AgCl1 |
Synonyms |
U-251 MG AgCl1; U-251 MGAgCl1 |
Accession |
CVCL_5G63 |
Resource Identification Initiative |
To cite this cell line use: U-251MG AgCl1 (RRID:CVCL_5G63) |
Comments |
Population: Caucasian. Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872. |
Sequence variations |
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
|
Disease |
Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0021 (U-251MG) |
Sex of cell |
Male |
Age at sampling |
75Y |
Category |
Cancer cell line |
Publications | PubMed=2454731 Monica Nister, Towia Aron Libermann, Christer Betsholtz, Monica Pettersson, Lena Claesson-Welsh, Carl-Henrik Heldin, Joseph Schlessinger, Bengt Westermark; Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res. 48:3910-3918(1988) DOI=10.1016/B978-0-12-333530-2.50005-8 Monica Nister, Bengt Westermark; Human glioma cell lines. (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.17-42; Academic Press; New York; USA (1994) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_5G63
|
Encyclopedic resources |
Wikidata; Q54973553
|
Entry history |
Entry creation | 14-Dec-2015 |
Last entry update | 19-Dec-2024 |
Version number | 14 |
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