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Cellosaurus U-251MG AgCl1 (CVCL_5G63)

[Text version]
Cell line name U-251MG AgCl1
Synonyms U-251 MG AgCl1; U-251 MGAgCl1
Accession CVCL_5G63
Resource Identification Initiative To cite this cell line use: U-251MG AgCl1 (RRID:CVCL_5G63)
Comments Population: Caucasian.
Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0021 (U-251MG)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=2454731
Monica Nister, Towia Aron Libermann, Christer Betsholtz, Monica Pettersson, Lena Claesson-Welsh, Carl-Henrik Heldin, Joseph Schlessinger, Bengt Westermark;
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Cancer Res. 48:3910-3918(1988)

DOI=10.1016/B978-0-12-333530-2.50005-8
Monica Nister, Bengt Westermark;
Human glioma cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.17-42; Academic Press; New York; USA (1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5G63
Encyclopedic resources Wikidata; Q54973553
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number14