Cellosaurus cell line ROSA KIT D816V (CVCL

Cellosaurus ROSA KIT D816V (CVCL_5G50)

Cross-references
Cell line name	ROSA KIT D816V
Accession	CVCL_5G50
Resource Identification Initiative	To cite this cell line use: ROSA KIT D816V (RRID:CVCL_5G50)
Comments	Group: Patented cell line. Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4552. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6342; KIT (Note=With del 417-419 insY). Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168. Cell type: Mast cell; CL=CL_0000097.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_5G49 (ROSA KIT WT)
Sex of cell	Male
Age at sampling	<1D
Category	Transformed cell line
Publications	CLPUB00277 Saleh R. Isolation of new human mast cell lines expressing a functional IgE receptor and different types of KIT receptors, used as models for the study of allergy and mastocytosis. Thesis PhD (2013); Universite Paris Sud; Paris; France PubMed=24677542; DOI=10.1182/blood-2013-10-534685 Saleh R., Wedeh G., Herrmann H., Bibi S., Cerny-Reiterer S., Sadovnik I., Blatt K., Hadzijusufovic E., Jeanningros S., Blanc C., Legarff-Tavernier M., Chapiro E., N'Guyen Khac F., Subra F., Bonnemye P., Dubreuil P., Desplat V., Merle-Beral H., Willmann M., Rulicke T., Valent P., Arock M. A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection. Blood 124:111-120(2014) Patent=US10383955 Arock M., Valent P., Saleh R., Wedeh G., Auclair C. Human mast cell lines, preparation and uses. Patent number US10383955, 20-Aug-2019
Encyclopedic resources	Wikidata; Q54950836
Entry history
Entry creation	14-Dec-2015
Last entry update	10-Apr-2025
Version number	11