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Cellosaurus ROSA KIT D816V (CVCL_5G50)

[Text version]
Cell line name ROSA KIT D816V
Accession CVCL_5G50
Resource Identification Initiative To cite this cell line use: ROSA KIT D816V (RRID:CVCL_5G50)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4552.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6342; KIT (Note=With del 417-419 insY).
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Cell type: Mast cell; CL=CL_0000097.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5G49 (ROSA KIT WT)
Sex of cell Male
Age at sampling <1D
Category Transformed cell line
Publications

CLPUB00277
Rosine Saleh;
Isolation of new human mast cell lines expressing a functional IgE receptor and different types of KIT receptors, used as models for the study of allergy and mastocytosis.
Thesis PhD (2013); Universite Paris Sud; Paris; France

PubMed=24677542; DOI=10.1182/blood-2013-10-534685
Rosine Saleh, Ghaith Wedeh, Harald Herrmann, Siham Bibi, Sabine Cerny-Reiterer, Irina Sadovnik, Katharina Blatt, Emir Hadzijusufovic, Sylvie Jeanningros, Catherine Blanc, Magali Legarff-Tavernier ...Show all 22 authors... , Elise Chapiro, Florence N'Guyen Khac, Frederic Subra, Patrick Bonnemye, Patrice Dubreuil, Vanessa Desplat, Helene Merle-Beral, Michael Willmann, Thomas Rulicke, Peter Valent, Michel Arock; Show fewer authors
A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection.
Blood 124:111-120(2014)

Patent=US10383955
Michel Arock, Peter Valent, Rosine Saleh, Ghaith Wedeh, Christian Auclair;
Human mast cell lines, preparation and uses.
Patent number US10383955, 20-Aug-2019

Cross-references
Encyclopedic resources Wikidata; Q54950836
Entry history
Entry creation14-Dec-2015
Last entry update10-Apr-2025
Version number11