Cellosaurus logo
expasy logo

Cellosaurus PUC4-2 (CVCL_5A62)

[Text][XML][JSON]
Cell line name PUC4-2
Accession CVCL_5A62
Resource Identification Initiative To cite this cell line use: PUC4-2 (RRID:CVCL_5A62)
Comments Selected for resistance to: ChEBI; CHEBI_35668; 6-azauridine (6AUR).
Selected for resistance to: ChEBI; CHEBI_90284; Pyrazofurin (Pirazofurin; PF).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_5A61 (V79 A3)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=220255; DOI=10.1016/S0021-9258(17)30053-4
D. Parker Suttle, George Robert Stark;
Coordinate overproduction of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in hamster cells resistant to pyrazofurin and 6-azauridine.
J. Biol. Chem. 254:4602-4607(1979)

PubMed=2595452; DOI=10.1007/BF01534911
Mazin Butros Qumsiyeh, D. Parker Suttle;
Cytogenetic analysis of amplification and deamplification of UMP synthase genes in Chinese hamster cells.
Somat. Cell Mol. Genet. 15:503-512(1989)

Cross-references
Encyclopedic resources Wikidata; Q54948694
Entry history
Entry creation14-Dec-2015
Last entry update27-Nov-2025
Version number11