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Cellosaurus CHO 51D1 (CVCL_5A48)

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Cell line name CHO 51D1
Synonyms 51D1
Accession CVCL_5A48
Resource Identification Initiative To cite this cell line use: CHO 51D1 (RRID:CVCL_5A48)
Comments Doubling time: ~16 hours (PubMed=16522646).
Knockout cell: Method=Homologous recombination; UniProtKB; G3GTU6; Rad51d.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4386 (CHO-AA8)
Children:
CVCL_5A49 (CHO 51D1.3)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=16522646; DOI=10.1093/nar/gkl020; PMCID=PMC1390685
John M. Hinz, Robert S. Tebbs, Paul F. Wilson, Peter B. Nham, Edmund P. Salazar, Hatsumi Nagasawa, Salustra S. Urbin, Joel S. Bedford, Lawrence H. Thompson;
Repression of mutagenesis by Rad51D-mediated homologous recombination.
Nucleic Acids Res. 34:1358-1368(2006)

PubMed=20434408; DOI=10.1016/j.dnarep.2010.03.009; PMCID=PMC2893262
Paul F. Wilson, John M. Hinz, Salustra S. Urbin, Peter B. Nham, Lawrence H. Thompson;
Influence of homologous recombinational repair on cell survival and chromosomal aberration induction during the cell cycle in gamma-irradiated CHO cells.
DNA Repair 9:737-744(2010)

PubMed=22923057; DOI=10.3892/or.2012.1982
Stefan C. Genet, Junko Maeda, Hiroshi Fujisawa, Charles R. Yurkon, Yoshihiro Fujii, Ashley M. Romero, Paula C. Genik, Akira Fujimori, Hisashi Kitamura, Takamitsu A. Kato;
Comparison of cellular lethality in DNA repair-proficient or -deficient cell lines resulting from exposure to 70 MeV/n protons or 290 MeV/n carbon ions.
Oncol. Rep. 28:1591-1596(2012)

Cross-references
Encyclopedic resources Wikidata; Q54812552
Entry history
Entry creation14-Dec-2015
Last entry update27-Nov-2025
Version number11