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Cellosaurus CHO-xrs-1 (CVCL_5A38)

[Text version]
Cell line name CHO-xrs-1
Synonyms CHO xrs-1; CHO-XRS1; xrs-1; xrs1
Accession CVCL_5A38
Resource Identification Initiative To cite this cell line use: CHO-xrs-1 (RRID:CVCL_5A38)
Comments Characteristics: Sensitive to X-ray. Has a defect in double-strand break rejoining (PubMed=6513971).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=6197643; DOI=10.1016/0167-8817(83)90026-3
Penelope Ann Jeggo, Lynn M. Kemp;
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.
Mutat. Res. 112:313-327(1983)

PubMed=6513971; DOI=10.1016/0167-8817(84)90037-3
Lynn M. Kemp, Steven G. Sedgwick, Penelope Ann Jeggo;
X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining.
Mutat. Res. 132:189-196(1984)

PubMed=9032253; DOI=10.1128/mcb.17.3.1264; PMCID=PMC231851
Belinda K. Singleton, Anne Priestley, Herdis Steingrimsdottir, David Gell, Tracy Blunt, Stephen Philip Jackson, Alan R. Lehmann, Penelope Ann Jeggo;
Molecular and biochemical characterization of xrs mutants defective in Ku80.
Mol. Cell. Biol. 17:1264-1273(1997)

Cross-references
Encyclopedic resources Wikidata; Q54813129
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number8