Cellosaurus cell line AMC-HN-3 (CVCL

Cross-references
Cell line name	AMC-HN-3
Synonyms	Amc-HN-3; AMC-HN3; Asian Medical Center-Head and Neck cancer-3
Accession	CVCL_5961
Resource Identification Initiative	To cite this cell line use: AMC-HN-3 (RRID:CVCL_5961)
Comments	Population: Korean. Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Heterozygous (PubMed=24336076).
Disease	Laryngeal squamous cell carcinoma (NCIt: C4044) Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	63Y
Category	Cancer cell line
Publications	PubMed=9349880; DOI=10.3109/00016489709113477 Sang Yoon Kim, Kwang-Chol Chu, Hye Rim Lee, Kwang-Sun Lee, Thomas E. Carey; Establishment and characterization of nine new head and neck cancer cell lines. Acta Oto-Laryngol. 117:775-784(1997) PubMed=24336076; DOI=10.1038/cddis.2013.488; PMCID=PMC3877559 Jong-Lyel Roh, Eun Hye Kim, H.B. Park, Jin Young Park; The Hsp90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin increases cisplatin antitumor activity by inducing p53-mediated apoptosis in head and neck cancer. Cell Death Dis. 4:e956.1-e956.8(2013)
Cell line databases/resources	cancercelllines; CVCL_5961
Encyclopedic resources	Wikidata; Q54749709
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	18