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Cellosaurus KTCTL-53 (CVCL_5882)

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Cell line name KTCTL-53
Synonyms KTCTL53; KTCTL 53; RCC-KP
Accession CVCL_5882
Resource Identification Initiative To cite this cell line use: KTCTL-53 (RRID:CVCL_5882)
Comments Population: Caucasian.
Misspelling: KTCL53; Cosmic=972925; PubMed=7915601.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Val84Profs*73 (c.250_256del); Zygosity=Unspecified (PubMed=7915601).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): CLS=300254

Markers:
AmelogeninX,Y
CSF1PO9,10
D3S135816
D5S81812,13
D7S82012
D8S117910,14
D13S31711,12
D16S5399,12
D18S5113,14
D21S1130
FGA20,21
Penta D9,12
Penta E7,14
TH017,9.3
TPOX8
vWA17,18

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Publications

PubMed=7915601; DOI=10.1038/ng0594-85
James R. Gnarra, Kalman Tory, Yong-Kai Weng, Laura S. Schmidt, Ming Hui Wei, Hua Li, Farida Latif, Sue Liu, Fan Chen, Fuh-Mei Duh, Irina A. Lubensky ...Show all 24 authors... , Dah-Shuhn R. Duan, Charles Florence, Rudy Pozzatti, McClellan Milton Walther, Neil Harrison Bander, Herbert Barton Grossman, Hiltrud Brauch, Sigmund Pomer, James D. Brooks, William B. Isaacs, Michael I. Lerman, Berton Zbar, William Marston Linehan; Show fewer authors
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=8086765; DOI=10.1007/BF00252823
Andreas J. Gross, Michael Wolff, Joachim Fandrey, Wulf-Dietrich Ekkehard Miersch, Klaus-Peter Dieckmann, Wolfgang Jelkmann;
Prevalence of paraneoplastic erythropoietin production by renal cell carcinomas.
Clin. Investig. 72:337-340(1994)

PubMed=11929824
Richard Batrla, Michael Linnebacher, Wolfgang Rudy, Susanne Stumm, Diethelm Wallwiener, Brigitte Guckel;
CD40-expressing carcinoma cells induce down-regulation of CD40 ligand (CD154) and impair T-cell functions.
Cancer Res. 62:2052-2057(2002)

Cross-references
Cell line collections (Providers) CLS; 300254
Encyclopedic resources Wikidata; Q54900650
Polymorphism and mutation databases Cosmic; 972925
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21