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Cellosaurus Hep-70.4 (CVCL_5772)

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Cell line name Hep-70.4
Synonyms HEP-70.4; 70.4
Accession CVCL_5772
Resource Identification Initiative To cite this cell line use: Hep-70.4 (RRID:CVCL_5772)
Comments Transformant: ChEBI; CHEBI_34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Ala135Pro (c.403G>C); Zygosity=Heterozygous (PubMed=1382443).
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Cys138Trp (c.414C>G); Zygosity=Heterozygous (PubMed=1382443).
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=1382443; DOI=10.1002/mc.2940060210
Stefan Kress, Jorg Konig, Jurgen Schweizer, Heinz Lohrke, Richard Bauer-Hofmann, Michael Schwarz;
p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors.
Mol. Carcinog. 6:148-158(1992)

Cross-references
Cell line collections (Providers) CLS; 400207
Encyclopedic resources Wikidata; Q54882773
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number15