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Cellosaurus KYM-1D4 (CVCL_5616)

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Cell line name KYM-1D4
Accession CVCL_5616
Resource Identification Initiative To cite this cell line use: KYM-1D4 (RRID:CVCL_5616)
Comments Problematic cell line: Possibly misclassified. It is not certain that the parent cell line originate from a alveolar rhabdomyosarcoma (ARMS). It lacks the PAXA3-FOXO1 gene fusion characteristics of ARMS. Many papers classify it as an embryonal rhabdomyosarcoma (ERMS) and we accordingly describe it as such.
Population: Japanese.
Derived from site: In situ; Neck; UBERON=UBERON_0000974.
Sequence variations
  • Gene deletion; HGNC; HGNC:11103; SMARCB1; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3007 (KYM-1)
Sex of cell Male
Age at sampling 9M
Category Cancer cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=KYM-1D4
Publications

PubMed=1960402; DOI=10.1016/0022-1759(91)90239-C
Anthony Meager;
A cytotoxicity assay for tumour necrosis factor using a human rhabdomyosarcoma cell line.
J. Immunol. Methods 144:141-143(1991)

PubMed=10485267; DOI=10.1016/S0022-1759(99)00081-2
Anthony Meager;
A tumour necrosis factor-alpha (TNF-alpha) sensitive adherent KYM-1D4 derived cell line: use in TNF-alpha cytotoxicity assays in the presence of actinomycin D.
J. Immunol. Methods 227:197-198(1999)

Cross-references
Encyclopedic resources Wikidata; Q54900788
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20