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Cellosaurus XTC-2 (CVCL_5610)

[Text version]
Cell line name XTC-2
Synonyms LSTM-XL-2; XTC-YF; XTC; Xenopus Tadpole Carcass-2
Accession CVCL_5610
Resource Identification Initiative To cite this cell line use: XTC-2 (RRID:CVCL_5610)
Comments Group: Amphibian cell line.
Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
Doubling time: ~24 hours (DOI=10.17037/PUBS.04656048).
Karyotypic information: Diploid karyotype (PubMed=4708349).
Caution: According to RCB RCB0771 XTC-YF and XTC-2 are identical.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Xenopus laevis (African clawed frog) (NCBI Taxonomy: 8355)
Hierarchy Children:
Sex of cell Sex unspecified
Age at sampling Tadpole stage
Category Spontaneously immortalized cell line
Web pages http://wiki.xenbase.org/xenwiki/index.php/tissue_culture_of_Xenopus_cell_lines_S3,_XTC_(Stukenberg_lab)

PubMed=4708349; DOI=10.1007/BF01926785
Pudney M., Varma M.G.R., Leake C.J.
Establishment of a cell line (XTC-2) from the South African clawed toad, Xenopus laevis.
Experientia 29:466-467(1973)

Leake C.J.
Comparative studies on the infection of invertebrate and vertebrate cell lines with some arboviruses.
Thesis PhD (1977), London School of Hygiene and Tropical Medicine, United Kingdom

PubMed=2318264; DOI=10.1016/0014-4827(90)90083-M
Snoek G.T., Koster C.H., de Laat S.W., Heideveld M., Durston A.J., van Zoelen E.J.J.
Effects of cell heterogeneity on production of polypeptide growth factors and mesoderm-inducing activity by Xenopus laevis XTC cells.
Exp. Cell Res. 187:203-210(1990)

PubMed=1811155; DOI=10.1016/S0091-679X(08)60300-3
Smith J.C., Tata J.R.
Xenopus cell lines.
Methods Cell Biol. 36:635-654(1991)

PubMed=8052658; DOI=10.1073/pnas.91.16.7767
St Germain D.L., Schwartzman R.A., Croteau W., Kanamori A., Wang Z., Brown D.D., Galton V.A.
A thyroid hormone-regulated gene in Xenopus laevis encodes a type III iodothyronine 5-deiodinase.
Proc. Natl. Acad. Sci. U.S.A. 91:7767-7771(1994)

PubMed=33389257; DOI=10.1007/s10096-020-04106-0
Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)

Cell line collections (Providers) Kerafast; EMU029
RCB; RCB0771
Cell line databases/resources CLO; CLO_0050158
Encyclopedic resources Wikidata; Q54995074
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14