Cellosaurus logo
expasy logo

Cellosaurus XTC-2 (CVCL_5610)

[Text version]
Cell line name XTC-2
Synonyms LSTM-XL-2; XTC-YF; XTC; Xenopus Tadpole Carcass-2
Accession CVCL_5610
Resource Identification Initiative To cite this cell line use: XTC-2 (RRID:CVCL_5610)
Comments Group: Amphibian cell line.
Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
Doubling time: ~24 hours (DOI=10.17037/PUBS.04656048).
Karyotypic information: Diploid karyotype (PubMed=4708349).
Caution: According to RCB RCB0771 XTC-YF and XTC-2 are identical.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Xenopus laevis (African clawed frog) (NCBI Taxonomy: 8355)
Hierarchy Children:
CVCL_C0NH (XTC-2 BirAV5)CVCL_VQ56 (XTC-GTX-11)
Sex of cell Sex unspecified
Age at sampling Tadpole stage
Category Spontaneously immortalized cell line
Web pages Info; Xenbase; -; https://wiki.xenbase.org/xenwiki/index.php?title=Tissue_culture_of_Xenopus_cell_lines_S3,_XTC_(Stukenberg_lab)
Publications

PubMed=4708349; DOI=10.1007/BF01926785
Mary Pudney, M.G. Raja Varma, Colin James Leake;
Establishment of a cell line (XTC-2) from the South African clawed toad, Xenopus laevis.
Experientia 29:466-467(1973)

DOI=10.17037/PUBS.04656048
Colin James Leake;
Comparative studies on the infection of invertebrate and vertebrate cell lines with some arboviruses.
Thesis PhD (1977); London School of Hygiene and Tropical Medicine; London; United Kingdom

PubMed=2318264; DOI=10.1016/0014-4827(90)90083-M
Gerry T. Snoek, Cees H. Koster, Siegfried Wolfgang de Laat, Martin Heideveld, Antony J. Durston, Everardus Johannes Jacobus van Zoelen;
Effects of cell heterogeneity on production of polypeptide growth factors and mesoderm-inducing activity by Xenopus laevis XTC cells.
Exp. Cell Res. 187:203-210(1990)

PubMed=1811155; DOI=10.1016/S0091-679X(08)60300-3
Jim C. Smith, Jamshed Rustom Tata;
Xenopus cell lines.
Methods Cell Biol. 36:635-654(1991)

PubMed=8052658; DOI=10.1073/pnas.91.16.7767; PMCID=PMC44483
Donald L. St Germain, Robert A. Schwartzman, Walburga Croteau, Akira Kanamori, Zhou Wang, Donald David Brown, Valerie Anne Galton;
A thyroid hormone-regulated gene in Xenopus laevis encodes a type III iodothyronine 5-deiodinase.
Proc. Natl. Acad. Sci. U.S.A. 91:7767-7771(1994)

PubMed=33389257; DOI=10.1007/s10096-020-04106-0; PMCID=PMC7778494
Nathalie Wurtz, Gwilherm Penant, Priscilla Jardot, Nathalie Duclos, Bernard La Scola;
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)

Cross-references
Cell line collections (Providers) Kerafast; EMU039
RCB; RCB0771
Cell line databases/resources CLO; CLO_0050158
Encyclopedic resources Wikidata; Q54995074
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16