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Cellosaurus OPCT-2 (CVCL_5570)

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Cell line name OPCT-2
Synonyms OPCT 2; OPCT2
Accession CVCL_5570
Resource Identification Initiative To cite this cell line use: OPCT-2 (RRID:CVCL_5570)
Comments Doubling time: 1.8 +- 0.2 days (CelloPub=CLPUB00396).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5567 ! OPCN-2
Sex of cell Male
Age at sampling 58Y
Category Transformed cell line
Web pages Provider; BioIVT/Asterand; -; https://bioivt.com/opc-prostate-and-normal-cell-lines/
Publications

CLPUB00396
James F. Eliason, Panteli Theocharous, Bernadette Caroline Palazzolo, Aisha Mehmood;
Derivation and initial characterization of three new prostate cancer cell lines and three new immortalized normal prostate epithelial cell lines.
Proc. Am. Assoc. Cancer Res. 45:792-792(2004)

CLPUB00242
Bernadette Caroline Palazzolo, Henry Hong-Qiang Heng, Ramzi M. Mohammad, Panteli Theocharous, James F. Eliason;
Characterization of three pairs of prostate cells lines derived from tumor and adjacent normal tissues.
Proc. Am. Assoc. Cancer Res. 46:1974-1974(2005)

PubMed=28094783; DOI=10.1038/srep40633; PMCID=PMC5240554
Naomi Harner-Foreman, Jayakumar Vadakekolathu, Stephanie A. Laversin, Morgan G. Mathieu, Stephen Reeder, A. Graham Pockley, Robert C. Rees, David J. Boocock;
A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics.
Sci. Rep. 7:40633-40633(2017)

Cross-references
Encyclopedic resources Wikidata; Q54936472
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number21