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Cellosaurus IOSE-29 (CVCL_5535)

[Text version]
Cell line name IOSE-29
Synonyms IOSE 29; IOSE29; NFHIOSE-29; IOSE-Mar; IOSE-MAR
Accession CVCL_5535
Resource Identification Initiative To cite this cell line use: IOSE-29 (RRID:CVCL_5535)
Comments From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada.
Doubling time: 33.7 hours (PubMed=10329039).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5536 (IOSE-29EC)CVCL_2G67 (T29)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1326894; DOI=10.1016/S0002-9378(11)91579-8
Sarah L. Maines-Bandiera, Patricia A. Kruk, Nelly Auersperg;
Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix.
Am. J. Obstet. Gynecol. 167:729-735(1992)

PubMed=7967506
Nelly Auersperg, Sarah L. Maines-Bandiera, Helen G. Dyck, Patricia A. Kruk;
Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes.
Lab. Invest. 71:510-518(1994)

PubMed=10329039; DOI=10.1006/gyno.1999.5348
Patricia A. Kruk, Andrew Kent Godwin, Thomas C. Hamilton, Nelly Auersperg;
Telomeric instability and reduced proliferative potential in ovarian surface epithelial cells from women with a family history of ovarian cancer.
Gynecol. Oncol. 73:229-236(1999)

PubMed=10339573; DOI=10.1073/pnas.96.11.6249; PMCID=PMC26867
Nelly Auersperg, Jie Pan, Bryon D. Grove, Todd Peterson, Janet Fisher, Sarah L. Maines-Bandiera, Aruna Somasiri, Calvin D. Roskelley;
E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium.
Proc. Natl. Acad. Sci. U.S.A. 96:6249-6254(1999)

PubMed=19926575; DOI=10.1309/AJCPTK87EMMIKPFS; PMCID=PMC3040237
Melissa S. DeRycke, John D. Andersen, Katherine M. Harrington, Stefan Eduard Pambuccian, Steve E. Kalloger, Kristin L.M. Boylan, Peter Alexander Argenta, Amy Patrice Norden Skubitz;
S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival.
Am. J. Clin. Pathol. 132:846-856(2009)

PubMed=20204287; DOI=10.3892/or_00000728; PMCID=PMC2909445
Gregory T. Langland, Steven M. Yannone, Rachel A. Langland, Aki Nakao, Ying-Hui Guan, Sydney B.T. Long, Lien Vonguyen, David J. Chen, Joe W. Gray, Fan-Qing Chen;
Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities.
Oncol. Rep. 23:1021-1026(2010)

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023
Britta Stordal, Kirsten Timms, Angela Farrelly, Danielle Gallagher, Steven Busschots, Mickael Renaud, Julien Thery, Deborah Williams, Jennifer Potter, Thanh Tran, Greg Korpanty ...Show all 19 authors... , Mattia Cremona, Mark S. Carey, Jie Li, Yang Li, Ozlem Aslan, John J. O'Leary, Gordon B. Mills, Bryan T. Hennessy; Show fewer authors
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mol. Oncol. 7:567-579(2013)

Cross-references
Anatomy/cell type resources BTO; BTO_0004132
Encyclopedic resources Wikidata; Q54897886
Polymorphism and mutation databases IARC_TP53; 28486
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number22