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Cellosaurus WSU-HN31 (CVCL_5526)

[Text version]
Cell line name WSU-HN31
Synonyms HN31; Wayne State University-Head and Neck 31
Accession CVCL_5526
Resource Identification Initiative To cite this cell line use: WSU-HN31 (RRID:CVCL_5526)
Comments Part of: MD Anderson Cell Lines Project.
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Disease Pharyngeal squamous cell carcinoma (NCIt: C102872)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5525 ! WSU-HN30
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81812,13
D7S82010
D13S31711,12
D16S53911,12
TH017,9
TPOX6,11
vWA15,18

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=8001221; DOI=10.1093/carcin/15.12.2683
Yeudall W.A., Crawford R.Y., Ensley J.F., Robbins K.C.
MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma.
Carcinogenesis 15:2683-2686(1994)

PubMed=7705939; DOI=10.1002/ijc.2910610117
Cardinali M., Pietraszkiewicz H., Ensley J.F., Robbins K.C.
Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies.
Int. J. Cancer 61:98-103(1995)

PubMed=9389571; DOI=10.1002/(SICI)1097-0215(19971114)73:4<551::AID-IJC16>3.0.CO;2-C
Patel V., Jakus J., Harris C.M., Ensley J.F., Robbins K.C., Yeudall W.A.
Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck.
Int. J. Cancer 73:551-555(1997)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29156801; DOI=10.18632/oncotarget.21174
Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y., Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Encyclopedic resources Wikidata; Q54994488
Polymorphism and mutation databases Cosmic; 922085
Cosmic; 2043893
Cosmic; 2131845
Cosmic; 2439754
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19