| Cell line name |
WSU-HN6 |
| Synonyms |
HN6; Wayne State University-Head and Neck 6 |
| Accession |
CVCL_5516 |
| Resource Identification Initiative |
To cite this cell line use: WSU-HN6 (RRID:CVCL_5516) |
| Comments |
Part of: OPC-22 oral and pharyngeal cancer cell line panel. Omics: Genomics; Whole exome sequencing. |
| Sequence variations |
|
| Disease |
Tongue squamous cell carcinoma (NCIt: C4648) Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Sex of cell |
Male |
| Age at sampling |
Age unspecified |
| Category |
Cancer cell line |
| STR profile |
Source(s): PubMed=25275298
Markers:| Amelogenin | X,Y |
| CSF1PO | 11 |
| D3S1358 | 18 |
| D5S818 | 11 |
| D7S820 | 10,11 |
| D8S1179 | 13,14 |
| D13S317 | 13 |
| D16S539 | 10,12 |
| D18S51 | 13 |
| D21S11 | 32.2,33.2 |
| FGA | 21,25 |
| Penta D | 9 |
| Penta E | 8,14 |
| TH01 | 6,9 |
| TPOX | 8,10 |
| vWA | 18,19 |
Run an STR similarity search on this cell line |
| Publications | PubMed=8001221; DOI=10.1093/carcin/15.12.2683 William Andrew Yeudall, Rosalynn Y. Crawford, John F. Ensley, Keith Cranston Robbins; MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma. Carcinogenesis 15:2683-2686(1994) PubMed=7705939; DOI=10.1002/ijc.2910610117 Massimo Cardinali, Halina Pietraszkiewicz, John F. Ensley, Keith Cranston Robbins; Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies. Int. J. Cancer 61:98-103(1995) PubMed=9049184; DOI=10.1002/(SICI)1098-2744(199702)18:2<89::AID-MC4>3.0.CO;2-L William Andrew Yeudall, Judit Jakus, John F. Ensley, Keith Cranston Robbins; Functional characterization of p53 molecules expressed in human squamous cell carcinomas of the head and neck. Mol. Carcinog. 18:89-96(1997) PubMed=9389571; DOI=10.1002/(SICI)1097-0215(19971114)73:4<551::AID-IJC16>3.0.CO;2-C Vyomesh Patel, Judit Jakus, Candice M. Harris, John F. Ensley, Keith Cranston Robbins, William Andrew Yeudall; Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck. Int. J. Cancer 73:551-555(1997) PubMed=25275298; DOI=10.18632/oncotarget.2417; PMCID=PMC4253406 Daniel Martin, Martin Carlos Abba, Alfredo Alberto Molinolo, Lynn Vitale-Cross, Zhi-Yong Wang, Moraima Zaida, Naomi C. Delic, Yardena Samuels, J. Guy Lyons, Jorge Silvio Gutkind; The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies. Oncotarget 5:8906-8923(2014) |
| Cross-references |
| Encyclopedic resources |
Wikidata; Q54994490
|
| Polymorphism and mutation databases |
Cosmic; 922087
Cosmic; 2043895
Cosmic; 2296295
Cosmic; 2513907
|
| Entry history |
| Entry creation | 04-Apr-2012 |
| Last entry update | 10-Apr-2025 |
| Version number | 17 |
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