Cellosaurus cell line BEL-7402/5-FU (CVCL

Cellosaurus BEL-7402/5-FU (CVCL_5493)

Cross-references
Cell line name	BEL-7402/5-FU
Synonyms	Bel7402/5-FU; BEL-7402/FU; Bel/5Fu
Accession	CVCL_5493
Resource Identification Initiative	To cite this cell line use: BEL-7402/5-FU (RRID:CVCL_5493)
Comments	Problematic cell line: Contaminated. Parent cell line (BEL-7402) has been shown to be a HeLa derivative. Population: African American. Doubling time: 42.3 +- 3.3 hours (PubMed=23167424). Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Omics: Proteomics; Quantitative. Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_5492 (BEL-7402)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Publications	PubMed=16696913; DOI=10.3736/jcim20060309 Wei Gu, Ya-Ni Zhang, Bai Li, Jie Han, Bin-Bin Cheng, Chang-Quan Ling; Establishment of a multidrug-resistant cell line BEL-7402/5-FU of human hepatocellular carcinoma and its biological characteristics. Zhong Xi Yi Jie He Xue Bao 4:265-270(2006) PubMed=23167424; DOI=10.7314/APJCP.2012.13.9.4807 Wei Gu, Fan-Fu Fang, Bai Li, Bin-Bin Cheng, Chang-Quan Ling; Characterization and resistance mechanisms of a 5-fluorouracil-resistant hepatocellular carcinoma cell line. Asian Pac. J. Cancer Prev. 13:4807-4814(2012)
Chemistry resources	ChEMBL-Cells; CHEMBL4482981 ChEMBL-Targets; CHEMBL4483230 PubChem_Cell_line; CVCL_5493
Encyclopedic resources	Wikidata; Q54795970
Proteomic databases	PRIDE; PXD015917
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	21