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Cellosaurus SK-LC-2 (CVCL_5468)

[Text version]
Cell line name SK-LC-2
Synonyms SK LC 02; SK-LC2
Accession CVCL_5468
Resource Identification Initiative To cite this cell line use: SK-LC-2 (RRID:CVCL_5468)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Miscellaneous: STR profile and age/sex of donor from MSKCC antibody and bioresource core facility.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro85fs (c.253delC); Zygosity=Unspecified (PubMed=12794755).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX,Y
CSF1PO12
D2S133817,18
D3S135816
D5S81811,12
D7S8209
D8S117913,14
D13S31712
D16S53912
D18S5117
D19S43313,15.2
D21S1129
FGA20
TH019.3
TPOX8
vWA16

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Publications

PubMed=6208122; DOI=10.1089/hyb.1.1982.1.139
Bernd R. Anger, Kenneth Oliver Lloyd, Herbert Friedrich Oettgen, Lloyd John Old;
Mouse monoclonal IgM antibody against human lung cancer line SK-LC-3 with specificity for H(O) blood group antigen.
Hybridoma 1:139-147(1982)

PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720
Michael Jules Mattes, Carlos Cordon-Cardo, John L. Lewis Jr., Lloyd John Old, Kenneth Oliver Lloyd;
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2540905
Takashi Takahashi, Yuichi Obata, Yoshitaka Sekido, Toyoaki Hida, Ryuzo Ueda, Hiroyoshi Watanabe, Yutaka Ariyoshi, Takahiko Sugiura, Toshitada Takahashi;
Expression and amplification of myc gene family in small cell lung cancer and its relation to biological characteristics.
Cancer Res. 49:2683-2688(1989)

PubMed=2784858; DOI=10.1073/pnas.86.8.2804; PMCID=PMC287007
Alexander Knuth, Thomas Wolfel, Eva Klehmann-Hieb, Thierry Boon, Karl-Hermann Meyer zum Buschenfelde;
Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.
Proc. Natl. Acad. Sci. U.S.A. 86:2804-2808(1989)

PubMed=9636188; DOI=10.1073/pnas.95.13.7556; PMCID=PMC22681
Daniel H. Kaplan, Vijay Shankaran, Anand Shrikant Dighe, Elisabeth Stockert, Michel Aguet, Lloyd John Old, Robert David Schreiber;
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice.
Proc. Natl. Acad. Sci. U.S.A. 95:7556-7561(1998)

PubMed=12794755; DOI=10.1002/ijc.11184
Hideki Endoh, Yasushi Yatabe, Shigeki Shimizu, Kohei Tajima, Hiroyuki Kuwano, Takashi Takahashi, Tetsuya Mitsudomi;
RASSF1A gene inactivation in non-small cell lung cancer and its clinical implication.
Int. J. Cancer 106:45-51(2003)

Cross-references
Encyclopedic resources Wikidata; Q54953709
Polymorphism and mutation databases Cosmic; 1089233
IARC_TP53; 18799
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20