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Cellosaurus VACO 10MS (CVCL_5393)

[Text version]
Cell line name VACO 10MS
Synonyms VACO10MS; Vaco10MS; V10MS; VACO-10M; VACO10M; V10M; VACO 10; VACO10
Accession CVCL_5393
Resource Identification Initiative To cite this cell line use: VACO 10MS (RRID:CVCL_5393)
Comments Part of: AstraZeneca Colorectal cell line (AZCL) panel.
Doubling time: 36 hours (PubMed=6498841).
Microsatellite instability: Stable (MSS) (PubMed=24755471).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
Disease Cecum adenocarcinoma (NCIt: C5543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5394 ! VACO 10P
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=6498841
John A. McBain, James L. Weese, Lorraine Faxon Meisner, William H. Wolberg, James K.V. Willson;
Establishment and characterization of human colorectal cancer cell lines.
Cancer Res. 44:5813-5821(1984)

PubMed=7761852; DOI=10.1126/science.7761852
Sanford David Markowitz, Jing Wang, Lois Lemmermann Myeroff, Ramon Parsons, Lu-Zhe Sun, James D. Lutterbaugh, Robert S. Fan, Elizabeth Zborowska, Kenneth Wayne Kinzler, Bert Vogelstein, Michael G. Brattain, James K.V. Willson;
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
Science 268:1336-1338(1995)

PubMed=8755562; DOI=10.1073/pnas.93.15.7832; PMCID=PMC38834
Da-Cai Liu, Eric Pearlman, Eugenia Diaconu, Kun Guo, Hiroshi Mori, Tariq Haqqi, Sanford David Markowitz, James K.V. Willson, Man-Sun Sy;
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Proc. Natl. Acad. Sci. U.S.A. 93:7832-7837(1996)

PubMed=16418264; DOI=10.1073/pnas.0510146103; PMCID=PMC1327731
Ying Liu, Walter Fred Bodmer;
Analysis of p53 mutations and their expression in 56 colorectal cancer cell lines.
Proc. Natl. Acad. Sci. U.S.A. 103:976-981(2006)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
Karin Bracht, Angela M. Nicholls, Ying Liu, Walter Fred Bodmer;
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849
Andreas Schlicker, Garry Beran, Christine M. Chresta, Gael McWalter, Alison Pritchard, Susie Weston, Sarah Runswick, Sara Davenport, Kerry Heathcote, Denis Alferez Castro, George Orphanides ...Show all 13 authors... , Tim French, Lodewyk F.A. Wessels; Show fewer authors
Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
BMC Med. Genomics 5:66.1-66.15(2012)

PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Dmitri Mouradov, Clare Sloggett, Robert N. Jorissen, Christopher G. Love, Shan Li, Antony Wilks Burgess, Diego Arango, Robert L. Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor ...Show all 17 authors... , Jennifer L. Wilding, David C. Bicknell, Ian Philip Mark Tomlinson, Walter Fred Bodmer, John M. Mariadason, Oliver M. Sieber; Show fewer authors
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5393
ColonAtlas; VACO10
Encyclopedic resources Wikidata; Q54992654
Gene expression databases GEO; GSM784050
GEO; GSM1346859
GEO; GSM1374980
Polymorphism and mutation databases Cosmic; 948824
Cosmic; 986022
Cosmic; 1223152
Cosmic; 1312319
Cosmic; 2302023
Cosmic; 2760086
IARC_TP53; 21745
Progenetix; CVCL_5393
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28