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Cellosaurus Sez627 (CVCL_5364)

[Text version]
Cell line name Sez627
Synonyms Sez 627; SEZ 627; SEZ627; Sez627(+); Sez.627
Accession CVCL_5364
Resource Identification Initiative To cite this cell line use: Sez627 (RRID:CVCL_5364)
Comments Population: Japanese.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from sampling site: Peripheral blood. Cell type=T-cell.
Disease Primary cutaneous T-cell non-Hodgkin lymphoma (NCIt: C3467)
Primary cutaneous T-cell lymphoma (ORDO: Orphanet_171901)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A6TG (Sez627(-))
Sex of cell Female
Age at sampling 10Y
Category Cancer cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=Sez627

PubMed=3023492; DOI=10.1016/0022-1759(86)90236-X
Namiuchi S., Kumagai S., Sano H., Yodoi J., Uchiyama T., Ikai K., Imura H., Maeda M.
A human T cell line established from a patient with Sezary syndrome Application for assay of human interleukin 2 (IL-2).
J. Immunol. Methods 94:215-224(1986)

PubMed=3263317; DOI=10.1016/0165-2478(88)90170-8
Maeda M., Noma T., Hama K., Honjo T.
Application of a human T cell line derived from a Sezary syndrome patient for human interleukin 4 assay.
Immunol. Lett. 18:247-253(1988)

PubMed=16242045; DOI=10.1186/1742-4690-2-64
Taniguchi Y., Nosaka K., Yasunaga J.-I., Maeda M., Mueller N., Okayama A., Matsuoka M.
Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms.
Retrovirology 2:64.1-64.16(2005)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356
Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-I., Usami K., Shimizu A., Matsuoka M.
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cell line collections RCB; RCB3547
Encyclopedic resources Wikidata; Q54952868
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number12