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Cellosaurus KOC-7C (CVCL_5307)

[Text version]
Cell line name KOC-7C
Synonyms KOC-7c; KOC7C
Accession CVCL_5307
Resource Identification Initiative To cite this cell line use: KOC-7C (RRID:CVCL_5307)
Comments Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: 45.9 hours (CelloPub=CLPUB00067).
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; PTM; Phosphorylation; Quantitative.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
HLA typing Source: PubMed=9023415
Class I
HLA-AA*02:01,31:01
HLA-BB*51,52
Disease Ovarian clear cell adenocarcinoma (NCIt: C40078)
Clear cell adenocarcinoma of the ovary (ORDO: Orphanet_398971)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): PubMed=30485824

Markers:
AmelogeninX
CSF1PO11,12
D5S81811
D7S8208,11,12
D13S31711,12
D16S5399,12
D21S1131,32
TH017,9
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Naoko Seki, Tomoaki Hoshino, Megumi Kikuchi, Akihiro Hayashi, Kyogo Itoh;
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

CLPUB00067
Yoshihisa Tomioka;
Establishment and characterization of three human ovarian clear cell carcinoma cell lines (KOC-4c, KOC-5c, KOC-7c).
J. Kurume Med. Assoc. 61:323-333(1998)

PubMed=15534119; DOI=10.1158/1078-0432.CCR-04-0279
Yumi Takemoto, Hirohisa Yano, Seiya Momosaki, Sachiko Ogasawara, Naoyo Nishida, Sakiko Kojiro, Toshiharu Kamura, Masamichi Kojiro;
Antiproliferative effects of interferon-alphaCon1 on ovarian clear cell adenocarcinoma in vitro and in vivo.
Clin. Cancer Res. 10:7418-7426(2004)

PubMed=26388441; DOI=10.1016/j.cell.2015.08.056; PMCID=PMC4644236
Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller, Hua Jane Lou, Lara Perryman, Thomas R. Cox, Nevena Zivanovic, Antonio Palmeri, Agata Wesolowska-Andersen ...Show all 18 authors... , Manuela Helmer-Citterich, Jesper Ferkinghoff-Borg, Hiroaki Itamochi, Bernd Bodenmiller, Janine T. Erler, Benjamin E. Turk, Rune Linding; Show fewer authors
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.
Cell 163:202-217(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096; PMCID=PMC6481945
Eniko Papp, Dorothy Hallberg, Gottfried E. Konecny, Daniel C. Bruhm, Vilmos Adleff, Michael Noe, Ioannis Kagiampakis, Doreen Palsgrove, Dylan Conklin, Yasuto Kinose, James R. White ...Show all 18 authors... , Michael F. Press, Ronny I. Drapkin, Hariharan Easwaran, Stephen Bruce Baylin, Dennis Joseph Slamon, Victor E. Velculescu, Robert B. Scharpf; Show fewer authors
Integrated genomic, epigenomic, and expression analyses of ovarian cancer cell lines.
Cell Rep. 25:2617-2633(2018)

Cross-references
Anatomy/cell type resources BTO; BTO_0004970
Biological sample resources BioSample; SAMN02800474
Encyclopedic resources Wikidata; Q54900277
Gene expression databases GEO; GSM659380
Polymorphism and mutation databases Cosmic; 2074243
Cosmic; 2482706
Proteomic databases PRIDE; PXD000901
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20