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Cellosaurus Y-MESO-8D (CVCL_5189)

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Cell line name Y-MESO-8D
Accession CVCL_5189
Resource Identification Initiative To cite this cell line use: Y-MESO-8D (RRID:CVCL_5189)
Comments Population: Japanese.
Characteristics: While the primary tumor is biphasic this cell line shows sarcomatoid morphology.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Donor information: No history of asbestos exposure (PubMed=16630136).
Misspelling: ACC-MESO-8D; IARC_TP53=24551.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Pleural sarcomatoid mesothelioma (NCIt: C45663)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5188 ! Y-MESO-8A
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): RCB=RCB5665

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811,12
D7S82011
D13S3178,9
D16S53912
TH017,9
TPOX11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=16630136; DOI=10.1111/j.1349-7006.2006.00184.x; PMCID=PMC11158456
Noriyasu Usami, Takayuki Fukui, Masashi Kondo, Tetsuo Taniguchi, Toshihiko Yokoyama, Shoichi Mori, Kohei Yokoi, Yoshitsugu Horio, Kaoru Shimokata, Yoshitaka Sekido, Toyoaki Hida;
Establishment and characterization of four malignant pleural mesothelioma cell lines from Japanese patients.
Cancer Sci. 97:387-394(2006)

PubMed=17270034; DOI=10.1111/j.1349-7006.2006.00386.x; PMCID=PMC11158069
Tetsuo Taniguchi, Sivasundaram Karnan, Takayuki Fukui, Toshihiko Yokoyama, Hiroyuki Tagawa, Kohei Yokoi, Yuichi Ueda, Tetsuya Mitsudomi, Yoshitsugu Horio, Toyoaki Hida, Yasushi Yatabe ...Show all 13 authors... , Masao Seto, Yoshitaka Sekido; Show fewer authors
Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32.
Cancer Sci. 98:438-446(2007)

PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164
Hideki Murakami, Tetsuya Mizuno, Tetsuo Taniguchi, Makiko Fujii, Futoshi Ishiguro, Takayuki Fukui, Shinya Akatsuka, Yoshitsugu Horio, Toyoaki Hida, Yutaka Kondo, Shinya Toyokuni ...Show all 13 authors... , Hirotaka Osada, Yoshitaka Sekido; Show fewer authors
LATS2 is a tumor suppressor gene of malignant mesothelioma.
Cancer Res. 71:873-883(2011)

PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387
Shuhei Hakiri, Hirotaka Osada, Futoshi Ishiguro, Hideki Murakami, Yuko Murakami-Tonami, Kohei Yokoi, Yoshitaka Sekido;
Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells.
Cancer Sci. 106:990-999(2015)

Cross-references
Cell line collections (Providers) RCB; RCB5665
Cell line databases/resources cancercelllines; CVCL_5189
Encyclopedic resources Wikidata; Q54995160
Gene expression databases GEO; GSM552524
GEO; GSM850287
Polymorphism and mutation databases Cosmic; 2759225
IARC_TP53; 24551
Progenetix; CVCL_5189
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22