Cellosaurus cell line HCE-7 (CVCL

Cellosaurus HCE-7 (CVCL_5138)

Cross-references
Cell line name	HCE-7
Synonyms	HCE7; HCE-7 (NM); HCE-7(NM)
Accession	CVCL_5138
Resource Identification Initiative	To cite this cell line use: HCE-7 (RRID:CVCL_5138)
Comments	Population: African American. Characteristics: Established from a tumor transplanted in nude mice. Doubling time: 53 hours (PubMed=2415247). Omics: Genomics; DNA methylation analysis. Omics: Transcriptomics; Microarray. Omics: Variations; SNP array analysis. Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Disease	Esophageal squamous cell carcinoma (NCIt: C4024) Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_1271 ! HCE-4
Sex of cell	Female
Age at sampling	50Y
Category	Cancer cell line
Publications	PubMed=2415247 Susan P. Banks-Schlegel, Jesse Quintero; Growth and differentiation of human esophageal carcinoma cell lines. Cancer Res. 46:250-258(1986) PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X Susan P. Banks-Schlegel, Jesse Quintero; Human esophageal carcinoma cells have fewer, but higher affinity epidermal growth factor receptors. J. Biol. Chem. 261:4359-4362(1986) PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j Jacqueline Whang-Peng, Susan P. Banks-Schlegel, Elaine C. Lee; Cytogenetic studies of esophageal carcinoma cell lines. Cancer Genet. Cytogenet. 45:101-120(1990) PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 70:2158-2164(2010)
Cell line databases/resources	cancercelllines; CVCL_5138 Cell_Model_Passport; SIDM00067
Anatomy/cell type resources	BTO; BTO_0002818
Chemistry resources	PharmacoDB; HCE7_515_2019
Encyclopedic resources	Wikidata; Q54881852
Gene expression databases	ArrayExpress; E-MTAB-3610 GEO; GSM827169 GEO; GSM1669866
Polymorphism and mutation databases	Cosmic; 923187 Cosmic; 932975 Cosmic; 2668298 Progenetix; CVCL_5138
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	19