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Cellosaurus SNU-899 (CVCL_5105)

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Cell line name SNU-899
Synonyms SNU899; NCI-SNU-899
Accession CVCL_5105
Resource Identification Initiative To cite this cell line use: SNU-899 (RRID:CVCL_5105)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 48 hours (PubMed=10369293).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Arg (c.37G>C); ClinVar=VCV000035554; Zygosity=Heterozygous (DepMap=ACH-000692).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:06,02:06
HLA-BB*15:01,15:01
HLA-CC*04:01,04:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.85
East Asian, North62.64
East Asian, South35.88
South Asian0
European, North0
European, South0.63
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A6IV (SNU-899 R1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): KCLB=00899

Markers:
AmelogeninX
CSF1PO12
D3S135817
D5S81811
D7S82010,13
D13S3178
FGA21
TH019,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Publications

CLPUB00001
Kwang Hyun Kim, Phil-Sang Chung, Hyun Min Park, Chae-Seo Rhee, Jae-Gahb Park;
Establishment and characterization of cell lines derived from squamous cell carcinoma of the head and neck.
Korean J. Head Neck Oncol. 12:181-187(1996)

PubMed=10369293; DOI=10.1097/00005537-199906000-00025
Ja-Lok Ku, Woo-Ho Kim, Jae-Ho Lee, Hyun-Sook Park, Kwang Hyun Kim, Myung-Whun Sung, Jae-Gahb Park;
Establishment and characterization of human laryngeal squamous cell carcinoma cell lines.
Laryngoscope 109:976-982(1999)

CLPUB00626
Kyong-Myong Chon, Soo-Geun Wang, Byung-Joo Lee, Jin-Choon Lee, Hyoung-Joon Koo, Sun-He Kim;
Establishment of cisplatin resistant head and neck cancer cell lines and cross-resistance of docetaxel.
Korean J. Otolaryngol. 48:651-655(2005)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ja-Lok Ku, Jae-Gahb Park;
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=17923759; DOI=10.3346/jkms.2007.22.S.S73; PMCID=PMC2694390
Byung-Joo Lee, Bae-Hyuk Lee, Soo-Geun Wang, Jin-Choon Lee, Hwan-Jung Roh, Eui-Kyung Goh, Cheol-Min Kim, Eun-Sook Jun;
Change of the expression of human telomerase reverse transcriptase mRNA and human telomerase RNA after cisplatin and 5-fluorouracil exposure in head and neck squamous cell carcinoma cell lines.
J. Korean Med. Sci. 22 Suppl. 1:S73-S78(2007)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) KCLB; 00899
Cell line databases/resources cancercelllines; CVCL_5105
Cell_Model_Passport; SIDM00169
DepMap; ACH-000692
Anatomy/cell type resources BTO; BTO_0005925
Biological sample resources BioSample; SAMN10988086
Chemistry resources PharmacoDB; SNU899_1488_2019
Encyclopedic resources Wikidata; Q54955284
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887642
GEO; GSM888734
Polymorphism and mutation databases Cosmic; 934175
IARC_TP53; 30171
LiGeA; CCLE_315
Progenetix; CVCL_5105
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29