Cellosaurus cell line SNU-494 (CVCL

Cellosaurus SNU-494 (CVCL_5070)

Cross-references
Cell line name	SNU-494
Synonyms	SNU494
Accession	CVCL_5070
Resource Identification Initiative	To cite this cell line use: SNU-494 (RRID:CVCL_5070)
Comments	Part of: Seoul National University (SNU) cell line collection. Population: Korean. Doubling time: 120 hours (PubMed=12037578). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=12037578). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys238Tyr (c.713G>A); ClinVar=VCV000182935; Zygosity=Unspecified (PubMed=12037578).
Disease	Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	58Y
Category	Cancer cell line
Publications	PubMed=12037578; DOI=10.1007/s00441-001-0510-y Ja-Lok Ku, Kyong-Ah Yoon, Woo-Ho Kim, Jin-Young Jang, Kyung-Suk Suh, Sun-Whe Kim, Yong-Hyun Park, Jae-Gahb Park; Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene. Cell Tissue Res. 308:205-214(2002) PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416 Ja-Lok Ku, Jae-Gahb Park; Biology of SNU cell lines. Cancer Res. Treat. 37:1-19(2005) DOI=10.4172/2324-9293.1000104 Markus Udo Wagenhauser, Felix Ruckert, Marco Niedergethmann, Robert Grutzmann, Hans-Detlev Saeger; Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines. Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)
Cell line databases/resources	cancercelllines; CVCL_5070
Encyclopedic resources	Wikidata; Q54955214
Polymorphism and mutation databases	Cosmic; 707184 IARC_TP53; 16869
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	18