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Cellosaurus SNU-251 (CVCL_5040)

[Text version]
Cell line name SNU-251
Synonyms SNU251
Accession CVCL_5040
Resource Identification Initiative To cite this cell line use: SNU-251 (RRID:CVCL_5040)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 46 hours (PubMed=9299249).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Trp1815Ter (c.5445G>A); ClinVar=VCV000055581; Zygosity=Hemizygous or homozygous (PubMed=9299249).
  • Mutation; HGNC; HGNC:7127; MLH1; Simple; p.Ala723Asp (c.2168C>A); Zygosity=Heterozygous (PubMed=9299249).
Disease BRCA1 syndrome (NCIt: C36100)
Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Hereditary breast and ovarian cancer syndrome (ORDO: Orphanet_145)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): KCLB=00251; PubMed=22710073

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,22
D3S135815,16
D5S81811
D7S82010,12
D8S117911,13
D13S3179
D16S53911
D18S5114,15
D19S43313.2,14.2
D21S1130,31.2
FGA20
TH018
TPOX12
vWA15,18

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Publications

PubMed=9299249; DOI=10.1006/gyno.1997.4785
Ying Yuan, Woo-Ho Kim, Hye Seung Han, Jae-Ho Lee, Hyun-Sook Park, June-Key Chung, Soon-Beom Kang, Jae-Gahb Park;
Establishment and characterization of human ovarian carcinoma cell lines.
Gynecol. Oncol. 66:378-387(1997)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ja-Lok Ku, Jae-Gahb Park;
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023
Britta Stordal, Kirsten Timms, Angela Farrelly, Danielle Gallagher, Steven Busschots, Mickael Renaud, Julien Thery, Deborah Williams, Jennifer Potter, Thanh Tran, Greg Korpanty ...Show all 19 authors... , Mattia Cremona, Mark S. Carey, Jie Li, Yang Li, Ozlem Aslan, John J. O'Leary, Gordon B. Mills, Bryan T. Hennessy; Show fewer authors
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mol. Oncol. 7:567-579(2013)

Cross-references
Cell line collections (Providers) KCLB; 00251
Cell line databases/resources cancercelllines; CVCL_5040
Encyclopedic resources Wikidata; Q54955155
Experimental variables resources EFO; EFO_0022583
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26