| Cell line name |
SNU-1684 |
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| Synonyms |
SNU1684 |
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| Accession |
CVCL_5028 |
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| Resource Identification Initiative |
To cite this cell line use: SNU-1684 (RRID:CVCL_5028) |
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| Comments |
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 53 hours (PubMed=20176655).
Microsatellite instability: Instable (MSI-high) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156. |
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| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg554Ter (c.1660C>T); ClinVar=VCV000000807; Zygosity=Heterozygous (PubMed=20176655).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Ile1557fs*1 (c.4669_4670delAT); Zygosity=Heterozygous (PubMed=20176655).
- Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Age at sampling |
43Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): KCLB=01684; PubMed=20176655; PubMed=25926053
Markers:| Amelogenin | X |
| CSF1PO | 9,10 |
| D2S1338 | 18,23 |
| D3S1358 | 17 |
| D5S818 | 10,11 |
| D7S820 | 9,13 |
| D8S1179 | 11,15 |
| D13S317 | 8 |
| D16S539 | 9,10 |
| D18S51 | 12 |
| D19S433 | 14,15.2 |
| D21S11 | 28 |
| FGA | 20,21 |
| TH01 | 9 |
| TPOX | 8,10 |
| vWA | 14,17 |
Run an STR similarity search on this cell line |
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| Publications | PubMed=20176655; DOI=10.1093/carcin/bgq043
Ja-Lok Ku, Young-Kyoung Shin, Duck-Woo Kim, Kyung-Hee Kim, Jin-Sung Choi, Sung-Hye Hong, You-Kyung Jeon, Sung-Hee Kim, Hong-Sun Kim, Jae-Hyun Park, Il-Jin Kim, Jae-Gahb Park;
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010) PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015) |
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| Cross-references |
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| Cell line collections (Providers) |
KCLB; 01684
|
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| Cell line databases/resources |
cancercelllines; CVCL_5028
ColonAtlas; SNU1684
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| Encyclopedic resources |
Wikidata; Q54955125
|
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| Gene expression databases |
GEO; GSM1448205
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| Polymorphism and mutation databases |
Cosmic; 1322293
IARC_TP53; 28481
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 24 |
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