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Cellosaurus SNU-1684 (CVCL_5028)

[Text version]
Cell line name SNU-1684
Synonyms SNU1684
Accession CVCL_5028
Resource Identification Initiative To cite this cell line use: SNU-1684 (RRID:CVCL_5028)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 53 hours (PubMed=20176655).
Microsatellite instability: Instable (MSI-high) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Arg554Ter (c.1660C>T); ClinVar=VCV000000807; Zygosity=Heterozygous (PubMed=20176655).
  • Mutation; HGNC; 583; APC; Simple; p.Ile1557fs*1 (c.4669_4670delAT); Zygosity=Heterozygous (PubMed=20176655).
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): KCLB=01684; PubMed=20176655; PubMed=25926053

Markers:
AmelogeninX
CSF1PO9,10
D2S133818,23
D3S135817
D5S81810,11
D7S8209,13
D8S117911,15
D13S3178
D16S5399,10
D18S5112
D19S43314,15.2
D21S1128
FGA20,21
TH019
TPOX8,10
vWA14,17

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Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) KCLB; 01684
Cell line databases/resources cancercelllines; CVCL_5028
ColonAtlas; SNU1684
Encyclopedic resources Wikidata; Q54955125
Gene expression databases GEO; GSM1448205
Polymorphism and mutation databases Cosmic; 1322293
IARC_TP53; 28481
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number22